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10.1016/j.semcdb.2020.05.018

http://scihub22266oqcxt.onion/10.1016/j.semcdb.2020.05.018
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suck abstract from ncbi


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pmid32553580      Semin+Cell+Dev+Biol 2021 ; 111 (ä): 101-107
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  • An Arms Race between the Nonsense-mediated mRNA Decay Pathway and Viral Infections #MMPMID32553580
  • Leon K; Ott M
  • Semin Cell Dev Biol 2021[Mar]; 111 (ä): 101-107 PMID32553580show ga
  • The Nonsense-mediated mRNA Decay (NMD) pathway is an RNA quality control pathway conserved among eukaryotic cells. While historically thought to predominantly recognize transcripts with premature termination codons, it is now known that the NMD pathway plays a variety of roles, from homeostatic events to control of viral pathogens. In this review we highlight the reciprocal interactions between the host NMD pathway and viral pathogens, which have shaped both the host antiviral defense and viral pathogenesis.
  • |*Nonsense Mediated mRNA Decay[MESH]
  • |Codon, Nonsense[MESH]
  • |Host-Pathogen Interactions/genetics[MESH]
  • |Humans[MESH]
  • |Protein Binding[MESH]
  • |Protein Biosynthesis[MESH]
  • |RNA Helicases/genetics/metabolism[MESH]
  • |RNA, Messenger/*genetics/metabolism[MESH]
  • |RNA, Viral/*genetics/metabolism[MESH]
  • |RNA-Binding Proteins/*genetics/metabolism[MESH]
  • |Ribosomes/genetics/metabolism[MESH]
  • |Signal Transduction[MESH]
  • |Trans-Activators/genetics/metabolism[MESH]
  • |Viral Proteins/*genetics/metabolism[MESH]
  • |Virus Diseases/*genetics/metabolism/pathology/virology[MESH]


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