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10.4269/ajtmh.20-0467

http://scihub22266oqcxt.onion/10.4269/ajtmh.20-0467
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32553046!7410463!32553046
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suck abstract from ncbi


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pmid32553046      Am+J+Trop+Med+Hyg 2020 ; 103 (2): 558-560
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  • Emergence of Undetectable Malaria Parasites: A Threat under the Radar amid the COVID-19 Pandemic? #MMPMID32553046
  • Beshir KB; Grignard L; Hajissa K; Mohammed A; Nurhussein AM; Ishengoma DS; Lubis IND; Drakeley CJ; Sutherland CJ
  • Am J Trop Med Hyg 2020[Aug]; 103 (2): 558-560 PMID32553046show ga
  • Rapid diagnostic tests (RDTs) play a critical role in malaria diagnosis and control. The emergence of Plasmodium falciparum parasites that can evade detection by RDTs threatens control and elimination efforts. These parasites lack or have altered genes encoding histidine-rich proteins (HRPs) 2 and 3, the antigens recognized by HRP2-based RDTs. Surveillance of such parasites is dependent on identifying false-negative RDT results among suspected malaria cases, a task made more challenging during the current pandemic because of the overlap of symptoms between malaria and COVID-19, particularly in areas of low malaria transmission. Here, we share our perspective on the emergence of P. falciparum parasites lacking HRP2 and HRP3, and the surveillance needed to identify them amid the COVID-19 pandemic.
  • |Africa[MESH]
  • |Antigens, Protozoan/analysis[MESH]
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*epidemiology[MESH]
  • |Diagnostic Tests, Routine/*methods[MESH]
  • |Humans[MESH]
  • |Malaria, Falciparum/*diagnosis/epidemiology[MESH]
  • |Pandemics[MESH]
  • |Plasmodium falciparum/*isolation & purification[MESH]
  • |Pneumonia, Viral/*epidemiology[MESH]
  • |Protozoan Proteins/analysis[MESH]


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