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10.1111/dth.13829 http://scihub22266oqcxt.onion/10.1111/dth.13829 32542964!7323008!32542964     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dermatol+Ther 2020 ; 33 (5): e13829 Nephropedia Template TP {{tp|p=32542964|t=2020. Treatment of COVID 19-Repurposing drugs commonly used in dermatology |pdf=|usr=}}{{32542964}} gab.com Text Treatment of COVID 19-Repurposing drugs commonly used in dermatology JO: Dermatol Ther http://www.kidney.de/pget.php?&tw=1&pmid=32542964 #FOAvip For the last two decades, the outbreaks of diseases caused by coronaviruses and intermittent worldwide public health emergences have reminded us that they still represent a severe threat to global health. The recent outbreak of corona virus disease 19 (COVID-19) highlighted the urgent need for effective treatment, and initiated rapid search for therapies, able to counter the most severe disease effects. Many aspects of COVID-19 pathogenesis are unknown, but complex interplay of direct viral damage and immune response dysregulation is underline. Intensive research is undergoing for therapeutic targets of virus and high-efficiency and low toxicity targeted drugs. There is no available specific antiviral treatment of this disease, therefore repurposing of drugs already available for the treatment of other viral and autoimmune diseases has been a part of research efforts. Well known anti-inflammatory properties of chloroquine and hydroxychloroquine, agents widely used in dermatology, made them potential candidates for the treatment of COVID-19. We review pathogenesis and clinical characteristic of COVID-19, as well as treatment options that have been under evaluation in past several months. In addition, we focus more on chloroquine and hydroxychloroquine, their pharmacological properties, clinical utility, and current recommendations for their use in COVID-19. Twit Text FOAVip Treatment of COVID 19-Repurposing drugs commonly used in dermatology ????Dermatol Ther http://www.kidney.de/pget.php?&tw=1&pmid=32542964 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32542964 #FOAvip English Wikipedia <ref>{{Cite pmid|32542964}}</ref> Treatment of COVID 19-Repurposing drugs commonly used in dermatology #MMPMID32542964 Stojkovic-Filipovic J; Bosic M Dermatol Ther 2020[Sep]; 33 (5): e13829 PMID32542964show ga For the last two decades, the outbreaks of diseases caused by coronaviruses and intermittent worldwide public health emergences have reminded us that they still represent a severe threat to global health. The recent outbreak of corona virus disease 19 (COVID-19) highlighted the urgent need for effective treatment, and initiated rapid search for therapies, able to counter the most severe disease effects. Many aspects of COVID-19 pathogenesis are unknown, but complex interplay of direct viral damage and immune response dysregulation is underline. Intensive research is undergoing for therapeutic targets of virus and high-efficiency and low toxicity targeted drugs. There is no available specific antiviral treatment of this disease, therefore repurposing of drugs already available for the treatment of other viral and autoimmune diseases has been a part of research efforts. Well known anti-inflammatory properties of chloroquine and hydroxychloroquine, agents widely used in dermatology, made them potential candidates for the treatment of COVID-19. We review pathogenesis and clinical characteristic of COVID-19, as well as treatment options that have been under evaluation in past several months. In addition, we focus more on chloroquine and hydroxychloroquine, their pharmacological properties, clinical utility, and current recommendations for their use in COVID-19. |*COVID-19 Drug Treatment[MESH] |*Dermatology[MESH] |*Drug Repositioning[MESH] |*SARS-CoV-2[MESH] |Antiviral Agents/therapeutic use[MESH] |COVID-19/complications[MESH] |Chloroquine/adverse effects/therapeutic use[MESH] |Humans[MESH]Treatment of COVID 19-Repurposing drugs commonly used in dermatology (epmc).pdf DeepDyve Pubget Overpricing