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10.1002/cyto.a.24172

http://scihub22266oqcxt.onion/10.1002/cyto.a.24172
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32542842!7323417!32542842
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suck abstract from ncbi


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pmid32542842      Cytometry+A 2020 ; 97 (8): 772-776
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  • Lymphocyte Subset Counts in COVID-19 Patients: A Meta-Analysis #MMPMID32542842
  • Huang W; Berube J; McNamara M; Saksena S; Hartman M; Arshad T; Bornheimer SJ; O'Gorman M
  • Cytometry A 2020[Aug]; 97 (8): 772-776 PMID32542842show ga
  • A reduced peripheral blood absolute lymphocyte count with an elevated neutrophil count has been a consistent observation in hospitalized coronavirus disease 2019 (COVID-19) patients. In this brief meta-analysis, the reduction of lymphocyte subset counts in COVID-19 patients was investigated across 20 peer-reviewed studies meeting criteria for reporting lymphocyte subset counts and COVID-19 disease severity. CD4+ T cell, CD8+ T cell, B cell, NK cell, and total lymphocyte cell counts all showed statistically significant reduction in patients with severe/critical COVID-19 disease compared to mild/moderate disease. T-cell subsets showed the largest standardized magnitude of change. In some studies, multivariate analysis has shown that CD4 and/or CD8 T-cells counts are independently predictive of patient outcomes. (c) 2020 International Society for Advancement of Cytometry.
  • |B-Lymphocytes/*cytology[MESH]
  • |Betacoronavirus[MESH]
  • |CD4-Positive T-Lymphocytes/*cytology[MESH]
  • |CD8-Positive T-Lymphocytes/*cytology[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*blood[MESH]
  • |Humans[MESH]
  • |Killer Cells, Natural/*cytology[MESH]
  • |Lymphocyte Count[MESH]
  • |Neutrophils/cytology[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*blood[MESH]
  • |SARS-CoV-2[MESH]


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