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10.1097/MEG.0000000000001804 http://scihub22266oqcxt.onion/10.1097/MEG.0000000000001804 32541245!ä!32541245 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 253.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32541245.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Eur+J+Gastroenterol+Hepatol 2020 ; 32 (9): 1251-1255 Nephropedia Template TP {{tp|p=32541245|t=2020. Immune monitoring of a child with autoimmune hepatitis and type 1 diabetes during COVID-19 infection |pdf=|usr=}}{{32541245}} gab.com Text Immune monitoring of a child with autoimmune hepatitis and type 1 diabetes during COVID-19 infection JO: Eur J Gastroenterol Hepatol http://www.kidney.de/pget.php?&tw=1&pmid=32541245 #FOAvip Immunocompromised patients may be at increased risk to develop COVID-19 during the 2019 beta-coronavirus infection. We present the unique opportunity we had to monitor the liver, IL-6 and immune cell course before, during and after COVID-19 in a boy with autoimmune hepatitis (AIH) and type 1 diabetes (T1D). CD4 and CD8 T cells frequencies decreased because of prednisolone, followed by a plateauing increase whereas CD19CD20 B cell increased strongly and was unaffected by COVID-19 infection. Moreover, the percentage of activated CD8 T cells expressing HLA-DR (CD8HLA-DR) increased during COVID-19 and subsided after its clearance. Total regulatory T cells (Tregs: CD4CD25CD127FOXP3) remained stable. Although activated Tregs (CD4CD45RAFOXP3) strongly increased upon prednisolone, it decreased afterwards. Furthermore, regulatory B cells (Bregs: CD19CD20CD24CD38) declined sharply owing to prednisolone. Serum IL-6 remained undetectable at all times. We demonstrated for the first time immune monitoring in a child with AIH and T1D before, during and after COVID-19. We hypothesize that continuing with low level of prednisolone without azathioprine may have abrogated activated Tregs, Bregs and IL-6 production and therefore permitting the activation of CD8 T cells, clearing the virus. Twit Text FOAVip Immune monitoring of a child with autoimmune hepatitis and type 1 diabetes during COVID-19 infection ????Eur J Gastroenterol Hepatol http://www.kidney.de/pget.php?&tw=1&pmid=32541245 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32541245 #FOAvip English Wikipedia <ref>{{Cite pmid|32541245}}</ref> Immune monitoring of a child with autoimmune hepatitis and type 1 diabetes during COVID-19 infection #MMPMID32541245 Yuksel M; Akturk H; Arikan C Eur J Gastroenterol Hepatol 2020[Sep]; 32 (9): 1251-1255 PMID32541245show ga Immunocompromised patients may be at increased risk to develop COVID-19 during the 2019 beta-coronavirus infection. We present the unique opportunity we had to monitor the liver, IL-6 and immune cell course before, during and after COVID-19 in a boy with autoimmune hepatitis (AIH) and type 1 diabetes (T1D). CD4 and CD8 T cells frequencies decreased because of prednisolone, followed by a plateauing increase whereas CD19CD20 B cell increased strongly and was unaffected by COVID-19 infection. Moreover, the percentage of activated CD8 T cells expressing HLA-DR (CD8HLA-DR) increased during COVID-19 and subsided after its clearance. Total regulatory T cells (Tregs: CD4CD25CD127FOXP3) remained stable. Although activated Tregs (CD4CD45RAFOXP3) strongly increased upon prednisolone, it decreased afterwards. Furthermore, regulatory B cells (Bregs: CD19CD20CD24CD38) declined sharply owing to prednisolone. Serum IL-6 remained undetectable at all times. We demonstrated for the first time immune monitoring in a child with AIH and T1D before, during and after COVID-19. We hypothesize that continuing with low level of prednisolone without azathioprine may have abrogated activated Tregs, Bregs and IL-6 production and therefore permitting the activation of CD8 T cells, clearing the virus. |*Betacoronavirus[MESH] |CD4-Positive T-Lymphocytes[MESH] |CD8-Positive T-Lymphocytes[MESH] |COVID-19[MESH] |Child, Preschool[MESH] |Coronavirus Infections/complications/*immunology/*therapy[MESH] |Diabetes Mellitus, Type 1/complications/*immunology/therapy[MESH] |Hepatitis, Autoimmune/complications/*immunology/therapy[MESH] |Humans[MESH] |Lymphocyte Count[MESH] |Male[MESH] |Monitoring, Immunologic[MESH] |Pandemics[MESH] |Pneumonia, Viral/complications/*immunology/*therapy[MESH]Immune monitoring of a child with autoimmune hepatitis and type 1 diab(epmc).pdf DeepDyve Pubget Overpricing