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10.1016/j.vaccine.2020.06.007 http://scihub22266oqcxt.onion/10.1016/j.vaccine.2020.06.007 32540271!7269942!32540271     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Vaccine 2020 ; 38 (33): 5085-5088 Nephropedia Template TP {{tp|p=32540271|t=2020. COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies?|pdf=|usr=}}{{32540271}} gab.com Text COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies JO: Vaccine http://www.kidney.de/pget.php?&tw=1&pmid=32540271 #FOAvip While a human challenge study holds the prospect of accelerating the development of a vaccine for the coronavirus SARS-CoV-2, it may be opposed due to risks of harm to participants and researchers. Given the increasing number of human deaths and severe disruption to lives worldwide, we argue that a SARS-CoV-2 challenge study is ethically justifiable as its social value substantially outweighs the risks. Such a study should therefore be seriously considered as part of the global research response towards the COVID-19 pandemic. In this paper, we contribute to the debate by addressing the misperception that a challenge study for the coronavirus would lower scientific and ethical standards for vaccine research and development, and examine how it could be ethically conducted. We also set out information that needs to be disclosed to prospective participants to obtain their consent. Twit Text FOAVip COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies ????Vaccine http://www.kidney.de/pget.php?&tw=1&pmid=32540271 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32540271 #FOAvip English Wikipedia <ref>{{Cite pmid|32540271}}</ref> COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge studies? #MMPMID32540271 Schaefer GO; Tam CC; Savulescu J; Voo TC Vaccine 2020[Jul]; 38 (33): 5085-5088 PMID32540271show ga While a human challenge study holds the prospect of accelerating the development of a vaccine for the coronavirus SARS-CoV-2, it may be opposed due to risks of harm to participants and researchers. Given the increasing number of human deaths and severe disruption to lives worldwide, we argue that a SARS-CoV-2 challenge study is ethically justifiable as its social value substantially outweighs the risks. Such a study should therefore be seriously considered as part of the global research response towards the COVID-19 pandemic. In this paper, we contribute to the debate by addressing the misperception that a challenge study for the coronavirus would lower scientific and ethical standards for vaccine research and development, and examine how it could be ethically conducted. We also set out information that needs to be disclosed to prospective participants to obtain their consent. |Betacoronavirus[MESH] |Biomedical Research/*ethics[MESH] |COVID-19[MESH] |COVID-19 Vaccines[MESH] |Coronavirus Infections/*prevention & control[MESH] |Humans[MESH] |Informed Consent[MESH] |Pandemics/ethics/*prevention & control[MESH] |Pneumonia, Viral/*prevention & control[MESH] |Risk[MESH] |SARS-CoV-2[MESH] |Vaccination/*ethics[MESH]COVID-19 vaccine development: Time to consider SARS-CoV-2 challenge st(epmc).pdf DeepDyve Pubget Overpricing