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10.1016/j.bjorl.2020.05.001

http://scihub22266oqcxt.onion/10.1016/j.bjorl.2020.05.001
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32534982!7247498!32534982
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suck abstract from ncbi


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pmid32534982      Braz+J+Otorhinolaryngol 2020 ; 86 (4): 490-496
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  • Incomplete and late recovery of sudden olfactory dysfunction in COVID-19 #MMPMID32534982
  • Kosugi EM; Lavinsky J; Romano FR; Fornazieri MA; Luz-Matsumoto GR; Lessa MM; Piltcher OB; Sant'Anna GD
  • Braz J Otorhinolaryngol 2020[Jul]; 86 (4): 490-496 PMID32534982show ga
  • INTRODUCTION: Sudden olfactory dysfunction is a new symptom related to COVID-19, with little data on its duration or recovery rate. OBJECTIVE: To characterize patients with sudden olfactory dysfunction during the COVID-19 pandemic, especially their recovery data. METHODS: An online survey was conducted by the Brazilian Society of Otorhinolaryngology and Cervico-Facial Surgery, and Brazilian Academy of Rhinology, including doctors who assessed sudden olfactory dysfunction patients starting after February 1st, 2020. Participants were posteriorly asked by e-mail to verify data on the recovery of sudden olfactory loss and test for COVID-19 at the end of the data collection period. RESULTS: 253 sudden olfactory dysfunction patients were included, of which 59.1% were females with median age of 36 years, with a median follow-up period of 31 days. 183 patients (72.3%) had been tested for COVID-19, and of those 145 (79.2%) tested positive. Patients that tested positive for COVID-19 more frequently showed non-specific inflammatory symptoms (89.7% vs. 73.7%; p=0.02), a lower rate of total recovery of sudden olfactory dysfunction (52.6% vs. 70.3%; p=0.05) and a longer duration to achieve total recovery (15 days vs. 10 days; p=0.0006) than the ones who tested negative for COVID-19. Considering only positive-COVID-19 patients, individuals with sudden hyposmia completely recovered more often than the ones with sudden anosmia (68.4% vs. 50.0%; p=0.04). CONCLUSION: Positive-COVID-19 patients with sudden olfactory dysfunction showed lower total recovery rate and longer duration than negative-COVID-19 patients. Additionally, total recovery was seen more frequently in positive-COVID-19 patients with sudden hyposmia than the ones with sudden anosmia.
  • |*Betacoronavirus[MESH]
  • |*Pandemics[MESH]
  • |Adult[MESH]
  • |Brazil[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/complications/*diagnosis/epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Olfaction Disorders/*etiology[MESH]
  • |Pneumonia, Viral/complications/*diagnosis/epidemiology[MESH]


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