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10.1016/j.chest.2020.05.583

http://scihub22266oqcxt.onion/10.1016/j.chest.2020.05.583
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32534909!7287448!32534909
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suck abstract from ncbi


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pmid32534909      Chest 2020 ; 158 (4): e143-e146
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  • First Detection of SARS-CoV-2 by Real-Time Reverse Transcriptase-Polymerase Chain Reaction Assay in Pleural Fluid #MMPMID32534909
  • Mei F; Bonifazi M; Menzo S; Di Marco Berardino A; Sediari M; Paolini L; Re A; Gonnelli F; Duranti C; Grilli M; Vennarucci GS; Latini MA; Zuccatosta L; Gasparini S
  • Chest 2020[Oct]; 158 (4): e143-e146 PMID32534909show ga
  • Coronavirus disease 2019 (COVID-19) is a pandemic infection due to the spread of a novel coronavirus (severe acute respiratory syndrome coronavirus 2), resulting in a wide range of clinical features, from asymptomatic carriers to ARDS. The gold standard for diagnosis is nucleic acid detection by real-time reverse transcriptase-polymerase chain reaction in nasopharyngeal swabs. However, due to limitations in this technique's sensitivity, thoracic imaging plays a crucial, complementary role in diagnostic evaluation and also allows for detection of atypical findings and potential alternative targets for sampling (eg, pleural effusion). Although less common, pleural involvement has been described in a minority of patients. This report describes the first case of reverse transcriptase-polymerase chain reaction detection of severe acute respiratory syndrome coronavirus 2 in pleural fluid obtained by means of ultrasound-guided thoracentesis, and its main characteristics are detailed. Pleural effusion is not a common finding in COVID-19 infection, but a prompt recognition of this potential localization may be useful to optimize diagnostic evaluation as well as the management of these patients.
  • |*Clinical Laboratory Techniques[MESH]
  • |Aged[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Coronavirus Infections/complications/*diagnosis[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Pleural Effusion/*virology[MESH]
  • |Pneumonia, Viral/complications/*diagnosis[MESH]
  • |Real-Time Polymerase Chain Reaction[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]


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