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10.1016/j.mehy.2020.109957 http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.109957 32531538!7274964!32531538     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Hypotheses 2020 ; 144 (ä): 109957 Nephropedia Template TP {{tp|p=32531538|t=2020. Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection?|pdf=|usr=}}{{32531538}} gab.com Text Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection JO: Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=32531538 #FOAvip SARS-CoV-2 or COVID-19 is representing the major global burden that implicated more than 4.7 million infected cases and 310 thousand deaths worldwide in less than 6 months. The prevalence of this pandemic disease is expected to rise every day. The challenge is to control its rapid spread meanwhile looking for a specific treatment to improve patient outcomes. Hesperidin is a classical herbal medicine used worldwide for a long time with an excellent safety profile. Hesperidin is a well-known herbal medication used as an antioxidant and anti-inflammatory agent. Available shreds of evidence support the promising use of hesperidin in prophylaxis and treatment of COVID 19. Herein, we discuss the possible prophylactic and treatment mechanisms of hesperidin based on previous and recent findings. Hesperidin can block coronavirus from entering host cells through ACE2 receptors which can prevent the infection. Anti-viral activity of hesperidin might constitute a treatment option for COVID-19 through improving host cellular immunity against infection and its good anti-inflammatory activity may help in controlling cytokine storm. Hesperidin mixture with diosmin co-administrated with heparin protect against venous thromboembolism which may prevent disease progression. Based on that, hesperidin might be used as a meaningful prophylactic agent and a promising adjuvant treatment option against SARS-CoV-2 infection. Twit Text FOAVip Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection ????Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=32531538 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32531538 #FOAvip English Wikipedia <ref>{{Cite pmid|32531538}}</ref> Is hesperidin essential for prophylaxis and treatment of COVID-19 Infection? #MMPMID32531538 Haggag YA; El-Ashmawy NE; Okasha KM Med Hypotheses 2020[Nov]; 144 (ä): 109957 PMID32531538show ga SARS-CoV-2 or COVID-19 is representing the major global burden that implicated more than 4.7 million infected cases and 310 thousand deaths worldwide in less than 6 months. The prevalence of this pandemic disease is expected to rise every day. The challenge is to control its rapid spread meanwhile looking for a specific treatment to improve patient outcomes. Hesperidin is a classical herbal medicine used worldwide for a long time with an excellent safety profile. Hesperidin is a well-known herbal medication used as an antioxidant and anti-inflammatory agent. Available shreds of evidence support the promising use of hesperidin in prophylaxis and treatment of COVID 19. Herein, we discuss the possible prophylactic and treatment mechanisms of hesperidin based on previous and recent findings. Hesperidin can block coronavirus from entering host cells through ACE2 receptors which can prevent the infection. Anti-viral activity of hesperidin might constitute a treatment option for COVID-19 through improving host cellular immunity against infection and its good anti-inflammatory activity may help in controlling cytokine storm. Hesperidin mixture with diosmin co-administrated with heparin protect against venous thromboembolism which may prevent disease progression. Based on that, hesperidin might be used as a meaningful prophylactic agent and a promising adjuvant treatment option against SARS-CoV-2 infection. |*COVID-19 Drug Treatment[MESH] |*Phytotherapy[MESH] |Angiotensin-Converting Enzyme 2/drug effects[MESH] |Anticoagulants/administration & dosage/therapeutic use[MESH] |Antiviral Agents/*therapeutic use[MESH] |COVID-19/complications/epidemiology/*prevention & control[MESH] |Cytokine Release Syndrome/drug therapy/prevention & control[MESH] |Diosmin/administration & dosage/therapeutic use[MESH] |Drug Therapy, Combination[MESH] |Heparin/administration & dosage/therapeutic use[MESH] |Hesperidin/administration & dosage/pharmacology/*therapeutic use[MESH] |Humans[MESH] |MAP Kinase Signaling System/drug effects[MESH] |Pandemics/*prevention & control[MESH] |Receptors, Virus/drug effects[MESH] |SARS-CoV-2/*drug effects[MESH] |Venous Thromboembolism/etiology/prevention & control[MESH]Is hesperidin essential for prophylaxis and treatment of COVID-19 Infe(epmc).pdf DeepDyve Pubget Overpricing