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10.1016/j.jaapos.2020.05.002

http://scihub22266oqcxt.onion/10.1016/j.jaapos.2020.05.002
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suck abstract from ncbi


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pmid32531341      J+AAPOS 2020 ; 24 (4): 212-215
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  • Ocular manifestations and viral shedding in tears of pediatric patients with coronavirus disease 2019: a preliminary report #MMPMID32531341
  • Valente P; Iarossi G; Federici M; Petroni S; Palma P; Cotugno N; De Ioris MA; Campana A; Buzzonetti L
  • J AAPOS 2020[Aug]; 24 (4): 212-215 PMID32531341show ga
  • PURPOSE: To evaluate ocular manifestations and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) prevalence in the tears of children with coronavirus disease 2019 (COVID-19). METHODS: A total of 27 pediatric patients with confirmed COVID-19 infection hospitalized from March 16 to April 15, 2020, at the Bambino Gesu Children's Hospital were enrolled in the study. At admission, all patients showed ocular manifestations. Reverse transcriptase-polymerase chain reaction from nasopharyngeal and conjunctival swabs were performed every 2-3 days before discharge. RESULTS: Of the 27 patients, 4 (15%) were asymptomatic, 15 (56%) showed respiratory symptoms, and 8 (30%) had gastrointestinal symptoms. At admission, nasopharyngeal swabs were positive for COVID-19 in all patients; on the second swabs, 7 children (26%) tested negative, and 20 remained positive for COVID-19. Ocular manifestations consistent with mild viral conjunctivitis were observed in 4 patients (15%). At first conjunctival swab, 3 patients (11%), 1 symptomatic and 2 asymptomatic for ocular infection, had positive findings for COVID-19; 2 became negative on the second test and 1 on the third. CONCLUSIONS: In our study cohort, ocular manifestations of COVID-19 seem to have had a milder clinical course in pediatric patients than in adults. Despite the low prevalence and rapid regression of viral presence in the conjunctiva, SARS-CoV-2 transmission through tears may be possible, even in patients without apparent ocular involvement.
  • |*Pandemics[MESH]
  • |*Virus Shedding[MESH]
  • |COVID-19/*epidemiology/virology[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Conjunctiva/virology[MESH]
  • |Eye Infections, Viral/epidemiology/*virology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Infant, Newborn[MESH]
  • |Male[MESH]
  • |Prospective Studies[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]


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