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10.1111/1471-0528.16362

http://scihub22266oqcxt.onion/10.1111/1471-0528.16362
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32531146!7323034!32531146
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suck abstract from ncbi


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pmid32531146      BJOG 2020 ; 127 (11): 1324-1336
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  • Maternal transmission of SARS-COV-2 to the neonate, and possible routes for such transmission: a systematic review and critical analysis #MMPMID32531146
  • Walker KF; O'Donoghue K; Grace N; Dorling J; Comeau JL; Li W; Thornton JG
  • BJOG 2020[Oct]; 127 (11): 1324-1336 PMID32531146show ga
  • BACKGROUND: Early reports of COVID-19 in pregnancy described management by caesarean, strict isolation of the neonate and formula feeding. Is this practice justified? OBJECTIVE: To estimate the risk of the neonate becoming infected with SARS-CoV-2 by mode of delivery, type of infant feeding and mother-infant interaction. SEARCH STRATEGY: Two biomedical databases were searched between September 2019 and June 2020. SELECTION CRITERIA: Case reports or case series of pregnant women with confirmed COVID-19, where neonatal outcomes were reported. DATA COLLECTION AND ANALYSIS: Data were extracted on mode of delivery, infant infection status, infant feeding and mother-infant interaction. For reported infant infection, a critical analysis was performed to evaluate the likelihood of vertical transmission. MAIN RESULTS: Forty nine studies included information on mode of delivery and infant infection status for 655 women and 666 neonates. In all, 28/666 (4%) tested positive postnatally. Of babies born vaginally, 8/292 (2.7%) tested positivecompared with 20/374 (5.3%) born by Caesarean. Information on feeding and baby separation were often missing, but of reported breastfed babies 7/148 (4.7%) tested positive compared with 3/56 (5.3%) for reported formula fed ones. Of babies reported as nursed with their mother 4/107 (3.7%) tested positive, compared with 6/46 (13%) for those who were reported as isolated. CONCLUSIONS: Neonatal COVID-19 infection is uncommon, rarely symptomatic, and the rate of infection is no greater when the baby is born vaginally, breastfed or remains with the mother. TWEETABLE ABSTRACT: Risk of neonatal infection with COVID-19 by delivery route, infant feeding and mother-baby interaction.
  • |*Infant Formula[MESH]
  • |Betacoronavirus[MESH]
  • |Bottle Feeding/*statistics & numerical data[MESH]
  • |Breast Feeding/*statistics & numerical data[MESH]
  • |Breast Milk Expression[MESH]
  • |COVID-19[MESH]
  • |Cesarean Section/*statistics & numerical data[MESH]
  • |China/epidemiology[MESH]
  • |Coronavirus Infections/*epidemiology/*transmission[MESH]
  • |Delivery, Obstetric/statistics & numerical data[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Infant, Newborn[MESH]
  • |Infectious Disease Transmission, Vertical/*statistics & numerical data[MESH]
  • |Milk, Human[MESH]
  • |Mother-Child Relations[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/*transmission[MESH]
  • |Pregnancy[MESH]
  • |Pregnancy Complications, Infectious/*epidemiology[MESH]
  • |Risk Factors[MESH]


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