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10.1080/1120009X.2020.1775424

http://scihub22266oqcxt.onion/10.1080/1120009X.2020.1775424
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32530369!7298881!32530369
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suck abstract from ncbi


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pmid32530369      J+Chemother 2021 ; 33 (3): 193-197
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  • Lopinavir/ritonavir as a third agent in the antiviral regimen for SARS-CoV-2 infection #MMPMID32530369
  • Panagopoulos P; Petrakis V; Panopoulou M; Trypsianis G; Penlioglou T; Pnevmatikos I; Papazoglou D
  • J Chemother 2021[May]; 33 (3): 193-197 PMID32530369show ga
  • Corona Virus Disease (CoVID-19) is an emerging public health problem rapidly spread globally. New treatment options for patients with severe symptoms and ways of reducing transmission in the community are taken into consideration. A retrospective study was conducted in the Department of Infectious Diseases of Alexandroupolis (Greece) including 16 patients with CoVID-19. They were classified into two groups, A and B. Group A received lopinavir/ritonavir as a third agent in the antiviral regimen, while group B did not. Lymphocytes were more significantly increased in patients of group A. Ferritin serum levels were also decreased significantly in these patients. Number of days needed for a first negative result of Real Time- Polymerase Chain Reaction (RT-PCR) was lower for Group A. The present study suggests that lopinavir/ritonavir may reduce the viral carriage in a shorter period of time compared with other antiviral regimens. Further studies are needed in order to evaluate the effectiveness of lopinavir/ritonavir in the treatment of patients with SARS-CoV-2 infection.
  • |*COVID-19 Drug Treatment[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |COVID-19/virology[MESH]
  • |Drug Combinations[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Lopinavir/*therapeutic use[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Retrospective Studies[MESH]
  • |Ritonavir/*therapeutic use[MESH]


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