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10.1038/s41577-020-0348-8 http://scihub22266oqcxt.onion/10.1038/s41577-020-0348-8 32528136!7288618!32528136     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Immunol 2020 ; 20 (7): 442-447 Nephropedia Template TP {{tp|p=32528136|t=2020. Considering how biological sex impacts immune responses and COVID-19 outcomes |pdf=|usr=}}{{32528136}} gab.com Text Considering how biological sex impacts immune responses and COVID-19 outcomes JO: Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32528136 #FOAvip A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with the pathogenesis of other viral infections. Biological sex differences may manifest themselves in susceptibility to infection, early pathogenesis, innate viral control, adaptive immune responses or the balance of inflammation and tissue repair in the resolution of infection. We discuss available sex-disaggregated epidemiological data from the COVID-19 pandemic, introduce sex-differential features of immunity and highlight potential sex differences underlying COVID-19 severity. We propose that sex differences in immunopathogenesis will inform mechanisms of COVID-19, identify points for therapeutic intervention and improve vaccine design and increase vaccine efficacy. Twit Text FOAVip Considering how biological sex impacts immune responses and COVID-19 outcomes ????Nat Rev Immunol http://www.kidney.de/pget.php?&tw=1&pmid=32528136 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32528136 #FOAvip English Wikipedia <ref>{{Cite pmid|32528136}}</ref> Considering how biological sex impacts immune responses and COVID-19 outcomes #MMPMID32528136 Scully EP; Haverfield J; Ursin RL; Tannenbaum C; Klein SL Nat Rev Immunol 2020[Jul]; 20 (7): 442-447 PMID32528136show ga A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with the pathogenesis of other viral infections. Biological sex differences may manifest themselves in susceptibility to infection, early pathogenesis, innate viral control, adaptive immune responses or the balance of inflammation and tissue repair in the resolution of infection. We discuss available sex-disaggregated epidemiological data from the COVID-19 pandemic, introduce sex-differential features of immunity and highlight potential sex differences underlying COVID-19 severity. We propose that sex differences in immunopathogenesis will inform mechanisms of COVID-19, identify points for therapeutic intervention and improve vaccine design and increase vaccine efficacy. |Adaptive Immunity[MESH] |Age Factors[MESH] |Betacoronavirus/physiology[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology/immunology/pathology/physiopathology[MESH] |Female[MESH] |Humans[MESH] |Interferons/immunology[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*epidemiology/immunology/pathology/physiopathology[MESH] |SARS-CoV-2[MESH] |Severity of Illness Index[MESH] |Sex Factors[MESH]Considering how biological sex impacts immune responses and COVID-19 o(epmc).pdf DeepDyve Pubget Overpricing