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  • Genetic structure of SARS-CoV-2 reflects clonal superspreading and multiple independent introduction events, North-Rhine Westphalia, Germany, February and March 2020 #MMPMID32524946
  • Walker A; Houwaart T; Wienemann T; Vasconcelos MK; Strelow D; Senff T; Hulse L; Adams O; Andree M; Hauka S; Feldt T; Jensen BE; Keitel V; Kindgen-Milles D; Timm J; Pfeffer K; Dilthey AT
  • Euro Surveill 2020[Jun]; 25 (22): ä PMID32524946show ga
  • We whole-genome sequenced 55 SARS-CoV-2 isolates from Germany to investigate SARS-CoV-2 outbreaks in 2020 in the Heinsberg district and Dusseldorf. While the genetic structure of the Heinsberg outbreak indicates a clonal origin, reflecting superspreading dynamics from mid-February during the carnival season, distinct viral strains were circulating in Dusseldorf in March, reflecting the city's international links. Limited detection of Heinsberg strains in the Dusseldorf area despite geographical proximity may reflect efficient containment and contact-tracing efforts.
  • |*Pandemics[MESH]
  • |Betacoronavirus/*genetics/isolation & purification/pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques/*methods[MESH]
  • |Coronavirus Infections/*diagnosis/epidemiology[MESH]
  • |Disease Outbreaks[MESH]
  • |Genome, Viral/*genetics[MESH]
  • |Germany/epidemiology[MESH]
  • |Humans[MESH]
  • |Pneumonia, Viral/*diagnosis/epidemiology[MESH]
  • |RNA-Directed DNA Polymerase[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2[MESH]
  • |Whole Genome Sequencing/*methods[MESH]

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  • suck abstract from ncbi

    ä 22.25 2020