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Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Haemophilia 2020 ; 26 (5): 773-778 Nephropedia Template TP
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Registry of patients with congenital bleeding disorders and COVID-19 in Madrid #MMPMID32524712
Alvarez Roman MT; Butta Coll N; Garcia Barcenilla S; Perez Gonzalez L; de la Plaza Collazo I; De la Corte Rodriguez H; Romero Garrido JA; Martin Salces M; Rivas Pollmar MI; Cebanu T; Gonzalez-Zorrilla E; Acuna P; Monzon Manzano E; Rodriguez Merchan EC; Trelles Martinez R; Blanco Banares MJ; Gutierrez Alvarino M; Jimenez Yuste V
Haemophilia 2020[Sep]; 26 (5): 773-778 PMID32524712show ga
INTRODUCTION: We present the first registry of patients with congenital bleeding disorders and COVID-19. The study has been carried out in the Community of Madrid, which has the highest number of cases in Spain. The objective is to understand the incidence of COVID-19, the course of the disease if it occurs and the psychosocial and occupational impact on this population. METHODS: We included 345 patients (246 of haemophilia, 69 of von Willebrand Disease, two rare bleeding disorders and 28 carriers of haemophilia). A telephone survey was used to collect the data. RESULTS: Forty-two patients presented symptoms suggestive of infection by COVID-19, and in six cases, the disease was confirmed by RT-PCR. The cumulative incidence of our series was 1.73%. It is worth noting the complexity of the management of COVID-19 in two patients on prophylaxis with non-factor replacement therapy. Adherence to the prescribed treatment was maintained by 95.5% of patients. Although 94% were independent for daily living activities, 42.4% had a recognized disability and 58% required assistance, provided by the Madrid Haemophilia Association (Ashemadrid) in 75% of cases. Only 4.4% of consultations were held in person. CONCLUSIONS: Patients with congenital bleeding disorders infected with SARS-CoV-2 presented a mild course of the disease that did not require admission. Their identification and treatment by a specialist team from a Haemophilia Treatment Center are essential to make a correct assessment of the risk of haemorrhage/thrombosis. COVID-19 had a major impact on the psychosocial aspects of these patients which must be remedied with recovery plans.