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10.1007/s00705-020-04690-8 http://scihub22266oqcxt.onion/10.1007/s00705-020-04690-8 32524263!7286419!32524263     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Virol 2020 ; 165 (9): 2037-2043 Nephropedia Template TP {{tp|p=32524263|t=2020. Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway |pdf=|usr=}}{{32524263}} gab.com Text Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway JO: Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=32524263 #FOAvip Various strains of infectious bronchitis virus (IBV) cause different forms of infectious bronchitis with different clinical signs. Here, primary chicken embryo kidney (CEK) cells and specific-pathogen-free (SPF) chickens were infected with three pathogenic IBV strains, and it was observed that the TLR7-MYD88 pathway was inhibited but the TLR3-TIRF pathway was activated. After treatment with poly(I:C)-LMW, poly (I:C)-LMW/LyoVec, and Imiquimod, the replication of IBV was significantly suppressed after 24 h. However, treatment with TLR3 pathway inhibitors such as Pepinh-TRIF, celastrol, chloroquine, and BX795 resulted in increased replication of IBV after 36 h. These results also showed that chloroquine and celastrol were most effective inhibitors of the antiviral response at 48 hpi. Twit Text FOAVip Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway ????Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=32524263 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32524263 #FOAvip English Wikipedia <ref>{{Cite pmid|32524263}}</ref> Infectious bronchitis virus inhibits activation of the TLR7 pathway, but not the TLR3 pathway #MMPMID32524263 Zhu J; Xu S; Li X; Wang J; Jiang Y; Hu W; Ruan W Arch Virol 2020[Sep]; 165 (9): 2037-2043 PMID32524263show ga Various strains of infectious bronchitis virus (IBV) cause different forms of infectious bronchitis with different clinical signs. Here, primary chicken embryo kidney (CEK) cells and specific-pathogen-free (SPF) chickens were infected with three pathogenic IBV strains, and it was observed that the TLR7-MYD88 pathway was inhibited but the TLR3-TIRF pathway was activated. After treatment with poly(I:C)-LMW, poly (I:C)-LMW/LyoVec, and Imiquimod, the replication of IBV was significantly suppressed after 24 h. However, treatment with TLR3 pathway inhibitors such as Pepinh-TRIF, celastrol, chloroquine, and BX795 resulted in increased replication of IBV after 36 h. These results also showed that chloroquine and celastrol were most effective inhibitors of the antiviral response at 48 hpi. |Animals[MESH] |Chickens[MESH] |Coronavirus Infections/genetics/metabolism/*veterinary/virology[MESH] |Host-Pathogen Interactions[MESH] |Infectious bronchitis virus/genetics/isolation & purification/*physiology[MESH] |Poultry Diseases/genetics/*metabolism/virology[MESH] |Signal Transduction[MESH] |Toll-Like Receptor 3/genetics/*metabolism[MESH]Infectious bronchitis virus inhibits activation of the TLR7 pathway, b(epmc).pdf DeepDyve Pubget Overpricing