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10.1016/j.ijid.2020.06.006

http://scihub22266oqcxt.onion/10.1016/j.ijid.2020.06.006
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32522597!7834648!32522597
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suck abstract from ncbi


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pmid32522597      Int+J+Infect+Dis 2020 ; 99 (ä): 307-309
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  • Treatment of SARS-CoV-2 with high dose oral zinc salts: A report on four patients #MMPMID32522597
  • Finzi E
  • Int J Infect Dis 2020[Oct]; 99 (ä): 307-309 PMID32522597show ga
  • Coronavirus 2019 (COVID-19) is a pandemic with substantial mortality and no accepted therapy. We report here on four consecutive outpatients with clinical characteristics (CDC case definition) of and/or laboratory-confirmed COVID-19 who were treated with high dose zinc salt oral lozenges. All four patients experienced significant improvement in objective and symptomatic disease measures after one day of high dose therapy suggesting that zinc therapy was playing a role in clinical recovery. A mechanism for zinc's effects is proposed based on previously published studies on SARS- CoV-1, and randomized controlled trials assessing zinc shortening of common cold duration. The limited sample size and study design preclude a definitive statement about the effectiveness of zinc as a treatment for COVID-19 but suggest the variables to be addressed to confirm these initial findings in future trials.
  • |Adult[MESH]
  • |Betacoronavirus/*drug effects[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*drug therapy/virology[MESH]
  • |Dyspnea/drug therapy[MESH]
  • |Female[MESH]
  • |Gluconates/*administration & dosage[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Oxygen/*administration & dosage[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*drug therapy/virology[MESH]
  • |SARS-CoV-2[MESH]


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