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10.5543/tkda.2020.03374

http://scihub22266oqcxt.onion/10.5543/tkda.2020.03374
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32519978!ä!32519978

suck abstract from ncbi


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pmid32519978      Turk+Kardiyol+Dern+Ars 2020 ; 48 (4): 410-424
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  • COVID-19 (Sars-cov 2/Koronavirus-19) tedavisinde klinikte kullanilan geleneksel Cin tibbi bitkileri ve kardiyovaskuler sisteme etkileri #MMPMID32519978
  • Akalin E; Ekici M; Alan Z; Ozbir Elevli E; Yaman Bucak A; Aobuliaikemu N; Uresin AY
  • Turk Kardiyol Dern Ars 2020[Jun]; 48 (4): 410-424 PMID32519978show ga
  • OBJECTIVE: The aim of this study was to evaluate the effectiveness of plants used in the formulations of traditional Chinese medicine (TCM), which were also used in clinical trials to treat patients with the novel coronavirus COVID-19, and to assess their effects on the cardiovascular system. METHODS: A literature review of PubMed, ResearchGate, ScienceDirect, the Cochrane Library, and TCM monographs was conducted and the effects of the plants on the cardiovascular system and the mechanisms of action in COVID-19 treatment were evaluated. RESULTS: The mechanism of action, cardiovascular effects, and possible toxicity of 10 plants frequently found in TCM formulations that were used in the clinical treatment of COVID-19 were examined. CONCLUSION: TCM formulations that had been originally developed for earlier viral diseases have been used in COVID-19 treatment. Despite the effectiveness seen in laboratory and animal studies with the most commonly used plants in these formulations, the clinical studies are currently insufficient according to standard operating procedures. More clinical studies are needed to understand the safe clinical use of traditional plants.
  • |*Medicine, Chinese Traditional[MESH]
  • |Animals[MESH]
  • |Anti-Arrhythmia Agents/pharmacology/therapeutic use/toxicity[MESH]
  • |Anti-Inflammatory Agents/pharmacology/therapeutic use/toxicity[MESH]
  • |Anticholesteremic Agents/pharmacology/therapeutic use/toxicity[MESH]
  • |Antihypertensive Agents/pharmacology/therapeutic use/toxicity[MESH]
  • |Antiviral Agents/pharmacology/therapeutic use/toxicity[MESH]
  • |COVID-19[MESH]
  • |Calcium Channel Blockers/pharmacology/therapeutic use/toxicity[MESH]
  • |Cardiovascular System/*drug effects[MESH]
  • |Coronavirus Infections/*therapy[MESH]
  • |Drug Interactions[MESH]
  • |Drugs, Chinese Herbal/pharmacology/*therapeutic use/toxicity[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Platelet Aggregation Inhibitors/pharmacology/therapeutic use/toxicity[MESH]
  • |Pneumonia, Viral/*therapy[MESH]


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