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10.1186/s42358-020-00134-8

http://scihub22266oqcxt.onion/10.1186/s42358-020-00134-8
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suck abstract from ncbi


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pmid32517786      Adv+Rheumatol 2020 ; 60 (1): 32
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  • Revisiting hydroxychloroquine and chloroquine for patients with chronic immunity-mediated inflammatory rheumatic diseases #MMPMID32517786
  • Dos Reis Neto ET; Kakehasi AM; de Medeiros Pinheiro M; Ferreira GA; Marques CDL; da Mota LMH; Dos Santos Paiva E; Pileggi GCS; Sato EI; Reis APMG; Xavier RM; Provenza JR
  • Adv Rheumatol 2020[Jun]; 60 (1): 32 PMID32517786show ga
  • Hydroxychloroquine and chloroquine, also known as antimalarial drugs, are widely used in the treatment of rheumatic diseases and have recently become the focus of attention because of the ongoing COVID-19 pandemic. Rheumatologists have been using antimalarials to manage patients with chronic immune-mediated inflammatory rheumatic diseases for decades. It is an appropriate time to review their immunomodulatory and anti-inflammatory mechanisms impact on disease activity and survival of systemic lupus erythematosus patient, including antiplatelet effect, metabolic and lipid benefits. We also discuss possible adverse effects, adding a practical and comprehensive approach to monitoring rheumatic patients during treatment with these drugs.
  • |Antimalarials/*pharmacology[MESH]
  • |Antiphospholipid Syndrome/drug therapy/immunology[MESH]
  • |Antirheumatic Agents/therapeutic use[MESH]
  • |Arthritis, Rheumatoid/*drug therapy/immunology[MESH]
  • |COVID-19[MESH]
  • |Chloroquine/*pharmacology[MESH]
  • |Coronavirus Infections/drug therapy[MESH]
  • |Drug Eruptions/etiology[MESH]
  • |Drug Interactions[MESH]
  • |Female[MESH]
  • |Glucose/metabolism[MESH]
  • |Heart Diseases/chemically induced[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/*pharmacology[MESH]
  • |Lipids/blood[MESH]
  • |Lupus Erythematosus, Cutaneous/drug therapy/immunology[MESH]
  • |Lupus Erythematosus, Systemic/*drug therapy/immunology/mortality[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |Platelet Aggregation/drug effects[MESH]
  • |Pneumonia, Viral/drug therapy[MESH]
  • |Pregnancy[MESH]
  • |Renal Insufficiency/prevention & control[MESH]
  • |Retinal Diseases/chemically induced[MESH]


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