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10.1111/ggi.13960 http://scihub22266oqcxt.onion/10.1111/ggi.13960 32516861!7300699!32516861     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Geriatr+Gerontol+Int 2020 ; 20 (7): 704-708 Nephropedia Template TP {{tp|p=32516861|t=2020. Clinical characteristics and prognostic factors in COVID-19 patients aged /=80 years |pdf=|usr=}}{{32516861}} gab.com Text Clinical characteristics and prognostic factors in COVID-19 patients aged /=80 years JO: Geriatr Gerontol Int http://www.kidney.de/pget.php?&tw=1&pmid=32516861 #FOAvip AIM: The aim of the present study was to describe the clinical presentation of patients aged >/=80 years with coronavirus disease 2019 (COVID-19), and provide insights regarding the prognostic factors and the risk stratification in this population. METHODS: This was a single-center, retrospective, observational study, carried out in a referral center for COVID-19 in central Italy. We reviewed the clinical records of patients consecutively admitted for confirmed COVID-19 over a 1-month period (1-31 March 2020). We excluded asymptomatic discharged patients. We identified risk factors for death, by a uni- and multivariate Cox regression analysis. To improve model fitting and hazard estimation, continuous parameters where dichotomized by using Youden's index. RESULTS: Overall, 69 patients, aged 80-98 years, met the inclusion criteria and were included in the study cohort. The median age was 84 years (82-89 years is interquartile range); 37 patients (53.6%) were men. Globally, 14 patients (20.3%) presented a mild, 30 (43.5%) a severe and 25 (36.2%) a critical COVID-19 disease. A total of 23 (33.3%) patients had died at 30 days' follow up. Multivariate Cox regression analysis showed that severe dementia, pO(2) </=90 at admission and lactate dehydrogenase >464 U/L were independent risk factors for death. CONCLUSIONS: The present data suggest that risk of death could be not age dependent in patients aged >/=80 years, whereas severe dementia emerged is a relevant risk factor in this population. Severe COVID-19, as expressed by elevated lactate dehydrogenase and low oxygen saturation at emergency department admission, is associated with a rapid progression to death in these patients. Geriatr Gerontol Int 2020; **: **-**. Twit Text FOAVip Clinical characteristics and prognostic factors in COVID-19 patients aged /=80 years ????Geriatr Gerontol Int http://www.kidney.de/pget.php?&tw=1&pmid=32516861 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32516861 #FOAvip English Wikipedia <ref>{{Cite pmid|32516861}}</ref> Clinical characteristics and prognostic factors in COVID-19 patients aged /=80 years #MMPMID32516861 Covino M; De Matteis G; Santoro M; Sabia L; Simeoni B; Candelli M; Ojetti V; Franceschi F Geriatr Gerontol Int 2020[Jul]; 20 (7): 704-708 PMID32516861show ga AIM: The aim of the present study was to describe the clinical presentation of patients aged >/=80 years with coronavirus disease 2019 (COVID-19), and provide insights regarding the prognostic factors and the risk stratification in this population. METHODS: This was a single-center, retrospective, observational study, carried out in a referral center for COVID-19 in central Italy. We reviewed the clinical records of patients consecutively admitted for confirmed COVID-19 over a 1-month period (1-31 March 2020). We excluded asymptomatic discharged patients. We identified risk factors for death, by a uni- and multivariate Cox regression analysis. To improve model fitting and hazard estimation, continuous parameters where dichotomized by using Youden's index. RESULTS: Overall, 69 patients, aged 80-98 years, met the inclusion criteria and were included in the study cohort. The median age was 84 years (82-89 years is interquartile range); 37 patients (53.6%) were men. Globally, 14 patients (20.3%) presented a mild, 30 (43.5%) a severe and 25 (36.2%) a critical COVID-19 disease. A total of 23 (33.3%) patients had died at 30 days' follow up. Multivariate Cox regression analysis showed that severe dementia, pO(2) 464 U/L were independent risk factors for death. CONCLUSIONS: The present data suggest that risk of death could be not age dependent in patients aged >/=80 years, whereas severe dementia emerged is a relevant risk factor in this population. Severe COVID-19, as expressed by elevated lactate dehydrogenase and low oxygen saturation at emergency department admission, is associated with a rapid progression to death in these patients. Geriatr Gerontol Int 2020; **: **-**. |*Coronavirus Infections/blood/diagnosis/mortality/physiopathology[MESH] |*Pandemics[MESH] |*Pneumonia, Viral/blood/diagnosis/mortality/physiopathology[MESH] |Aged, 80 and over[MESH] |Betacoronavirus/isolation & purification[MESH] |COVID-19[MESH] |Critical Illness/epidemiology[MESH] |Dementia/*epidemiology[MESH] |Female[MESH] |Humans[MESH] |Hypoxia/*epidemiology[MESH] |Italy/epidemiology[MESH] |L-Lactate Dehydrogenase/*blood[MESH] |Male[MESH] |Mortality[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Assessment/*methods[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]Clinical characteristics and prognostic factors in COVID-19 patients a(epmc).pdf DeepDyve Pubget Overpricing