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10.1007/s13181-020-00790-8 http://scihub22266oqcxt.onion/10.1007/s13181-020-00790-8 32514696!7278768!32514696     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32514696&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       J+Med+Toxicol 2020 ; 16 (3): 314-320 Nephropedia Template TP {{tp|p=32514696|t=2020. Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam: an Increasing Concern in the COVID-19 Pandemic |pdf=|usr=}}{{32514696}} gab.com Text Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam: an Increasing Concern in the COVID-19 Pandemic JO: J Med Toxicol http://www.kidney.de/pget.php?&tw=1&pmid=32514696 #FOAvip INTRODUCTION: Recent attention on the possible use of hydroxychloroquine and chloroquine to treat COVID-19 disease has potentially triggered a number of overdoses from hydroxychloroquine. Toxicity from hydroxychloroquine manifests with cardiac conduction abnormalities, seizure activity, and muscle weakness. Recognizing this toxidrome and unique management of this toxicity is important in the COVID-19 pandemic. CASE REPORT: A 27-year-old man with a history of rheumatoid arthritis presented to the emergency department 7 hours after an intentional overdose of hydroxychloroquine. Initial presentation demonstrated proximal muscle weakness. The patient was found to have a QRS complex of 134 ms and QTc of 710 ms. He was treated with early orotracheal intubation and intravenous diazepam boluses. Due to difficulties formulating continuous diazepam infusions, we opted to utilize an intermitted intravenous bolus strategy that achieved similar effects that a continuous infusion would. The patient recovered without residual side effects. DISCUSSION: Hydroxychloroquine toxicity is rare but projected to increase in frequency given its selection as a potential modality to treat COVID-19 disease. It is important for clinicians to recognize the unique effects of hydroxychloroquine poisoning and initiate appropriate emergency maneuvers to improve the outcomes in these patients. Twit Text FOAVip Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam: an Increasing Concern in the COVID-19 Pandemic ????J Med Toxicol http://www.kidney.de/pget.php?&tw=1&pmid=32514696 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32514696 #FOAvip English Wikipedia <ref>{{Cite pmid|32514696}}</ref> Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepam: an Increasing Concern in the COVID-19 Pandemic #MMPMID32514696 Chai PR; Ferro EG; Kirshenbaum JM; Hayes BD; Culbreth SE; Boyer EW; Erickson TB J Med Toxicol 2020[Jul]; 16 (3): 314-320 PMID32514696show ga INTRODUCTION: Recent attention on the possible use of hydroxychloroquine and chloroquine to treat COVID-19 disease has potentially triggered a number of overdoses from hydroxychloroquine. Toxicity from hydroxychloroquine manifests with cardiac conduction abnormalities, seizure activity, and muscle weakness. Recognizing this toxidrome and unique management of this toxicity is important in the COVID-19 pandemic. CASE REPORT: A 27-year-old man with a history of rheumatoid arthritis presented to the emergency department 7 hours after an intentional overdose of hydroxychloroquine. Initial presentation demonstrated proximal muscle weakness. The patient was found to have a QRS complex of 134 ms and QTc of 710 ms. He was treated with early orotracheal intubation and intravenous diazepam boluses. Due to difficulties formulating continuous diazepam infusions, we opted to utilize an intermitted intravenous bolus strategy that achieved similar effects that a continuous infusion would. The patient recovered without residual side effects. DISCUSSION: Hydroxychloroquine toxicity is rare but projected to increase in frequency given its selection as a potential modality to treat COVID-19 disease. It is important for clinicians to recognize the unique effects of hydroxychloroquine poisoning and initiate appropriate emergency maneuvers to improve the outcomes in these patients. |*Suicide, Attempted[MESH] |Adult[MESH] |COVID-19[MESH] |Coronavirus Infections/*drug therapy[MESH] |Diazepam/*therapeutic use[MESH] |Drug Overdose/*drug therapy/epidemiology[MESH] |Drug-Related Side Effects and Adverse Reactions/*drug therapy[MESH] |Humans[MESH] |Hydroxychloroquine/*therapeutic use/*toxicity[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH] |Treatment Outcome[MESH]Intentional Hydroxychloroquine Overdose Treated with High-Dose Diazepa(epmc).pdf DeepDyve Pubget Overpricing