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Deprecated: Implicit conversion from float 300.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Clin+Rheumatol 2020 ; 39 (7): 2043-2047 Nephropedia Template TP
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The systemic sclerosis patient in the COVID-19 era: the challenging crossroad between immunosuppression, differential diagnosis and long-term psychological distress #MMPMID32514674
Orlandi M; Lepri G; Bruni C; Wang Y; Bartoloni A; Zammarchi L; Cometi L; Guiducci S; Matucci-Cerinic M; Bellando-Randone S
Clin Rheumatol 2020[Jul]; 39 (7): 2043-2047 PMID32514674show ga
COVID-19 is a world health emergency which may inevitably affect the management of a complex autoimmune disease such as systemic sclerosis (SSc). Several SSc patients are frail and, in this pandemic, need a careful protection. The COVID-19 infection might complicate the clinical scenario of interstitial lung disease (ILD) in SSc because it determines a severe pneumonia characterized by radiological features similar to SSc-ILD. The striking CT similarities between the 2 diseases make it difficult to distinguish a worsening of SSc-ILD from COVID-19-ILD superinfection. Moreover, other aspects, like isolation during lock down, may cause a significant psychological stress which will pile up on the already difficult contact with the patients for a routine check-up. Moreover, the drug shortage is a real problem in these times. For these reasons, the rheumatologist in daily clinical practice should carefully differentiate the possible COVID-19 infection in order to optimize the patient management. Therefore, the challenge in everyday life will be to achieve in due time the differential diagnosis as well as the long-term psychological impact.Key Points* SSc patients should be encouraged to continue their chronic therapy; in case of immunosuppressive therapy it must be discontinued for safety in case of COVID-19 infection.* Psychological support must be guaranteed to every SSc patients.* COVID-19 pneuminia is hard to distinguish from an interstitial lung disease due to SSc lung involvment.* Data sharing is fundamental for an optimal managment of SSc patients during COVID-19 pandemia.