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Dissecting antibody-mediated protection against SARS-CoV-2 #MMPMID32514035
Zohar T; Alter G
Nat Rev Immunol 2020[Jul]; 20 (7): 392-394 PMID32514035show ga
Understanding the properties and mechanisms by which antibodies provide protection is essential to defining immunity. Although neutralizing antibodies have been proposed as a potential key mechanism of protection against many viral pathogens, antibodies mediate additional immune functions that may have both protective and pathological consequences. Dissecting these properties against SARS-CoV-2 is likely necessary for defining metrics of immunity that will inform the design of vaccines and therapeutics and improve clinical management.