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10.1016/j.isci.2020.101215 http://scihub22266oqcxt.onion/10.1016/j.isci.2020.101215 32512383!7260547!32512383     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       iScience 2020 ; 23 (6): 101215 Nephropedia Template TP {{tp|p=32512383|t=2020. Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy |pdf=|usr=}}{{32512383}} gab.com Text Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy JO: iScience http://www.kidney.de/pget.php?&tw=1&pmid=32512383 #FOAvip The acute respiratory distress syndrome (ARDS) induced by SARS-CoV-2-mediated cytokine storm (CS) in lungs leads to the high mortality in COVID-19 patients. To reduce ARDS, an ideal approach is to diminish virus loading by activating immune cells for CS prevention or to suppress the overactive cytokine-releasing immune cells for CS inhibition. Here, a potential radiation-mediated CS regulation is raised by reevaluating the radiation-mediated pneumonia control in the 1920s, with the following latent advantages of lung radiotherapy (LR) in treatment of COVID-19: (1) radiation accesses poorly circulated tissue more efficiently than blood-delivered medications; (2) low-dose radiation (LDR)-mediated metabolic rewiring and immune cell activation inhibit virus loading; (3) pre-consumption of immune reserves by LDR decreases CS severity; (4) higherdose radiation (HDR) within lung-tolerable doses relieves CS by eliminating in situ overactive cytokine-releasing cells. Thus, LDR and HDR or combined with antiviral and life-supporting modalities may mitigate SARS-CoV-2 and other virus-mediated ARDS. Twit Text FOAVip Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy ????iScience http://www.kidney.de/pget.php?&tw=1&pmid=32512383 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32512383 #FOAvip English Wikipedia <ref>{{Cite pmid|32512383}}</ref> Mitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by Radiotherapy #MMPMID32512383 Li JJ iScience 2020[Jun]; 23 (6): 101215 PMID32512383show ga The acute respiratory distress syndrome (ARDS) induced by SARS-CoV-2-mediated cytokine storm (CS) in lungs leads to the high mortality in COVID-19 patients. To reduce ARDS, an ideal approach is to diminish virus loading by activating immune cells for CS prevention or to suppress the overactive cytokine-releasing immune cells for CS inhibition. Here, a potential radiation-mediated CS regulation is raised by reevaluating the radiation-mediated pneumonia control in the 1920s, with the following latent advantages of lung radiotherapy (LR) in treatment of COVID-19: (1) radiation accesses poorly circulated tissue more efficiently than blood-delivered medications; (2) low-dose radiation (LDR)-mediated metabolic rewiring and immune cell activation inhibit virus loading; (3) pre-consumption of immune reserves by LDR decreases CS severity; (4) higherdose radiation (HDR) within lung-tolerable doses relieves CS by eliminating in situ overactive cytokine-releasing cells. Thus, LDR and HDR or combined with antiviral and life-supporting modalities may mitigate SARS-CoV-2 and other virus-mediated ARDS. äMitigating Coronavirus-Induced Acute Respiratory Distress Syndrome by (epmc).pdf DeepDyve Pubget Overpricing