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10.1111/tid.13356

http://scihub22266oqcxt.onion/10.1111/tid.13356
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32510771!ä!32510771

suck abstract from ncbi


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pmid32510771      Transpl+Infect+Dis 2020 ; 22 (6): e13356
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  • COVID-19 in lung transplant recipients: A case series from Milan, Italy #MMPMID32510771
  • Morlacchi LC; Rossetti V; Gigli L; Amati F; Rosso L; Aliberti S; Nosotti M; Blasi F
  • Transpl Infect Dis 2020[Dec]; 22 (6): e13356 PMID32510771show ga
  • Limited data are currently available regarding the course of COVID-19 in lung and solid organ transplant recipients. We hereby present four cases of SARS-CoV-2 pneumonia in lung transplant recipients from our center, set in Milan, Italy. We reduced immunosuppressive regimen in all these patients, typically holding the antiproliferative agent and augmenting steroids; everybody received hydroxychloroquine, initial empiric antibiotic treatment with piperacillin/tazobactam, and high-dose low molecular weight heparin. Clinical course seemed favorable in three of our patients, but one of them deteriorated after 10 days of hospitalization, probably due to an acute form of graft dysfunction triggered both by COVID-19 and a nosocomial bacterial infection, and eventually died. Although short-term prognosis could be considered benign in the majority of our patients, we should carefully monitor these individuals in order to detect early sign of clinical deterioration and graft dysfunction in the next few months.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Lung Transplantation[MESH]
  • |Aged[MESH]
  • |Anti-Bacterial Agents/*therapeutic use[MESH]
  • |Anticoagulants/*therapeutic use[MESH]
  • |Blood Gas Analysis[MESH]
  • |COVID-19/immunology[MESH]
  • |Cystic Fibrosis/surgery[MESH]
  • |Deprescriptions[MESH]
  • |Enzyme Inhibitors/*therapeutic use[MESH]
  • |Female[MESH]
  • |Graft Rejection/prevention & control[MESH]
  • |Heparin, Low-Molecular-Weight/*therapeutic use[MESH]
  • |Humans[MESH]
  • |Hydroxychloroquine/*therapeutic use[MESH]
  • |Idiopathic Pulmonary Fibrosis/surgery[MESH]
  • |Immunosuppressive Agents/therapeutic use[MESH]
  • |Italy[MESH]
  • |Lung Diseases, Interstitial/surgery[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pulmonary Emphysema/surgery[MESH]
  • |SARS-CoV-2[MESH]


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