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10.3346/jkms.2020.35.e210

http://scihub22266oqcxt.onion/10.3346/jkms.2020.35.e210
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32508069!7279948!32508069
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suck abstract from ncbi


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pmid32508069      J+Korean+Med+Sci 2020 ; 35 (22): e210
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  • Therapeutic Temperature Modulation for a Critically Ill Patient with COVID-19 #MMPMID32508069
  • Jeong HG; Lee Y; Song KH; Hwang IC; Kim ES; Cho YJ
  • J Korean Med Sci 2020[Jun]; 35 (22): e210 PMID32508069show ga
  • We report a rapidly deteriorating coronavirus disease 2019 (COVID-19) patient, a-58-year-old woman, with severe acute respiratory distress syndrome and shock with hyperpyrexia up to 41.8 degrees C, probably due to the cytokine storm syndrome. Considering extracorporeal membrane oxygenation (ECMO) as the last resort, we applied therapeutic temperature modulation for management of hyperpyrexia. The patient demonstrated rapid improvement in oxygenation and shock after achieving normothermia, and fully recovered from COVID-19 three weeks later. Therapeutic temperature modulation may have successfully offloaded the failing cardiorespiratory system from metabolic cost and hyperinflammation induced by hyperpyrexia. The therapeutic temperature modulation can safely be applied in a specific group of patients with cytokine storm syndrome and hyperpyrexia, which may reduce the number of patients requiring ECMO in the global medical resource shortage.
  • |Betacoronavirus[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*pathology/*therapy[MESH]
  • |Critical Illness/therapy[MESH]
  • |Cryotherapy/*methods[MESH]
  • |Cytokine Release Syndrome/pathology[MESH]
  • |Female[MESH]
  • |Fever/*therapy[MESH]
  • |Humans[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*pathology/*therapy[MESH]
  • |SARS-CoV-2[MESH]


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