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10.1016/j.tim.2020.05.012 http://scihub22266oqcxt.onion/10.1016/j.tim.2020.05.012 32507543!7237910!32507543     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Microbiol 2020 ; 28 (8): 605-618 Nephropedia Template TP {{tp|p=32507543|t=2020. Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2 |pdf=|usr=}}{{32507543}} gab.com Text Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2 JO: Trends Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=32507543 #FOAvip SARS-Coronavirus-2 (SARS-CoV-2) causes Coronavirus disease 2019 (COVID-19), an infectious respiratory disease causing thousands of deaths and overwhelming public health systems. The international spread of SARS-CoV-2 is associated with the ease of global travel, and societal dynamics, immunologic naivete of the host population, and muted innate immune responses. Based on these factors and the expanding geographic scale of the disease, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic-the first caused by a coronavirus. In this review, we summarize the current epidemiological status of COVID-19 and consider the virological and immunological lessons, animal models, and tools developed in response to prior SARS-CoV and MERS-CoV outbreaks that can serve as resources for development of SARS-CoV-2 therapeutics and vaccines. In particular, we discuss structural insights into the SARS-CoV-2 spike protein, a major determinant of transmissibility, and discuss key molecular aspects that will aid in understanding and fighting this new global threat. Twit Text FOAVip Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2 ????Trends Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=32507543 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32507543 #FOAvip English Wikipedia <ref>{{Cite pmid|32507543}}</ref> Spiking Pandemic Potential: Structural and Immunological Aspects of SARS-CoV-2 #MMPMID32507543 Wang YT; Landeras-Bueno S; Hsieh LE; Terada Y; Kim K; Ley K; Shresta S; Saphire EO; Regla-Nava JA Trends Microbiol 2020[Aug]; 28 (8): 605-618 PMID32507543show ga SARS-Coronavirus-2 (SARS-CoV-2) causes Coronavirus disease 2019 (COVID-19), an infectious respiratory disease causing thousands of deaths and overwhelming public health systems. The international spread of SARS-CoV-2 is associated with the ease of global travel, and societal dynamics, immunologic naivete of the host population, and muted innate immune responses. Based on these factors and the expanding geographic scale of the disease, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic-the first caused by a coronavirus. In this review, we summarize the current epidemiological status of COVID-19 and consider the virological and immunological lessons, animal models, and tools developed in response to prior SARS-CoV and MERS-CoV outbreaks that can serve as resources for development of SARS-CoV-2 therapeutics and vaccines. In particular, we discuss structural insights into the SARS-CoV-2 spike protein, a major determinant of transmissibility, and discuss key molecular aspects that will aid in understanding and fighting this new global threat. |*Pandemics/prevention & control[MESH] |Animals[MESH] |Betacoronavirus/*chemistry/*immunology[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology/prevention & control/therapy/*virology[MESH] |Disease Models, Animal[MESH] |Humans[MESH] |Pneumonia, Viral/*epidemiology/prevention & control/therapy/*virology[MESH] |SARS-CoV-2[MESH]Spiking Pandemic Potential: Structural and Immunological Aspects of SA(epmc).pdf DeepDyve Pubget Overpricing