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10.1177/1078155220931921 http://scihub22266oqcxt.onion/10.1177/1078155220931921 32507102!ä!32507102 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Oncol+Pharm+Pract 2020 ; 26 (6): 1482-1485 Nephropedia Template TP {{tp|p=32507102|t=2020. Routine antiemetic prophylaxis with dexamethasone during COVID-19: Should oncologists reconsider?|pdf=|usr=}}{{32507102}} gab.com Text Routine antiemetic prophylaxis with dexamethasone during COVID-19: Should oncologists reconsider JO: J Oncol Pharm Pract http://www.kidney.de/pget.php?&tw=1&pmid=32507102 #FOAvip The ongoing pandemic caused by severe acute respiratory syndrome (SARS) coronavirus type 2 (SARS-CoV-2, also known as COVID-19) has caused unprecedented strain on the global healthcare system, causing thousands of deaths worldwide. Patients with underlying conditions such as cancer are at substantial risk of acquiring and dying from this novel coronavirus. Numerous reports have shown that infection with SARS-CoV-2 causes depletion of B- and T-lymphocytes, including CD4 and CD8 T-cells, and is associated with severe illness and death and that patients with higher lymphocyte levels may have better outcomes. Dexamethasone, a widely prescribed antiemetic for acute and delayed nausea and vomiting from a variety of cancer drugs, causes B and T cell depletion, which may augment immunosuppression. Since it seems that lymphocytes are vital in the immune response to novel coronavirus, oncologists should reconsider the routine use of prophylactic dexamethasone in uninfected patients, to avoid inducing lymphopenia, which may increase risk of infection or lead to inferior outcomes if a cancer patient subsequently becomes infected. Since many cancer drugs and malignant diseases inherently cause lymphopenia, further reduction of lymphocytes with dexamethasone should be avoided if possible and if safe and effective alternative antiemetics are available during the COVID-19 crisis. Twit Text FOAVip Routine antiemetic prophylaxis with dexamethasone during COVID-19: Should oncologists reconsider ????J Oncol Pharm Pract http://www.kidney.de/pget.php?&tw=1&pmid=32507102 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32507102 #FOAvip English Wikipedia <ref>{{Cite pmid|32507102}}</ref> Routine antiemetic prophylaxis with dexamethasone during COVID-19: Should oncologists reconsider? #MMPMID32507102 Marinella MA J Oncol Pharm Pract 2020[Sep]; 26 (6): 1482-1485 PMID32507102show ga The ongoing pandemic caused by severe acute respiratory syndrome (SARS) coronavirus type 2 (SARS-CoV-2, also known as COVID-19) has caused unprecedented strain on the global healthcare system, causing thousands of deaths worldwide. Patients with underlying conditions such as cancer are at substantial risk of acquiring and dying from this novel coronavirus. Numerous reports have shown that infection with SARS-CoV-2 causes depletion of B- and T-lymphocytes, including CD4 and CD8 T-cells, and is associated with severe illness and death and that patients with higher lymphocyte levels may have better outcomes. Dexamethasone, a widely prescribed antiemetic for acute and delayed nausea and vomiting from a variety of cancer drugs, causes B and T cell depletion, which may augment immunosuppression. Since it seems that lymphocytes are vital in the immune response to novel coronavirus, oncologists should reconsider the routine use of prophylactic dexamethasone in uninfected patients, to avoid inducing lymphopenia, which may increase risk of infection or lead to inferior outcomes if a cancer patient subsequently becomes infected. Since many cancer drugs and malignant diseases inherently cause lymphopenia, further reduction of lymphocytes with dexamethasone should be avoided if possible and if safe and effective alternative antiemetics are available during the COVID-19 crisis. |Antiemetics/*administration & dosage[MESH] |COVID-19[MESH] |Coronavirus Infections/*epidemiology[MESH] |Dexamethasone/*administration & dosage[MESH] |Female[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*epidemiology[MESH]Routine antiemetic prophylaxis with dexamethasone during COVID-19: Sho(epmc).pdf DeepDyve Pubget Overpricing