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10.1016/j.mehy.2020.109880

http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.109880
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32505846!7247463!32505846
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suck abstract from ncbi


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pmid32505846      Med+Hypotheses 2020 ; 144 (ä): 109880
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  • The use of ibuprofen to treat fever in COVID-19: A possible indirect association with worse outcome? #MMPMID32505846
  • Jamerson BD; Haryadi TH
  • Med Hypotheses 2020[Nov]; 144 (ä): 109880 PMID32505846show ga
  • Fever has been reported as a common symptom occurring in COVID-19 illness. Over the counter antipyretics such as ibuprofen and acetaminophen are often taken by individuals to reduce the discomfort of fever. Recently, the safety of ibuprofen in COVID-19 patients has been questioned due to anecdotal reports of worsening symptoms in previously healthy young adults. Studies show that ibuprofen demonstrates superior efficacy in fever reduction compared to acetaminophen. As fever may have benefit in shortening the duration of viral illness, it is plausible to hypothesize that the antipyretic efficacy of ibuprofen may be hindering the benefits of a fever response when taken during the early stages of COVID-19 illness.
  • |*COVID-19 Drug Treatment[MESH]
  • |Acetaminophen/therapeutic use[MESH]
  • |Antipyretics/*adverse effects/*therapeutic use[MESH]
  • |Fever/*drug therapy/physiopathology[MESH]
  • |Humans[MESH]
  • |Ibuprofen/*adverse effects/*therapeutic use[MESH]
  • |Models, Theoretical[MESH]
  • |Patient Safety[MESH]


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