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10.1016/j.mehy.2020.109907

http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.109907
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suck abstract from ncbi


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pmid32504927      Med+Hypotheses 2020 ; 143 (ä): 109907
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  • Periodontal pockets: A potential reservoir for SARS-CoV-2? #MMPMID32504927
  • Badran Z; Gaudin A; Struillou X; Amador G; Soueidan A
  • Med Hypotheses 2020[Oct]; 143 (ä): 109907 PMID32504927show ga
  • Periodontal pockets are the major clinical manifestation of Periodontitis, a chronic inflammatory oral disease affecting the teeth-supporting tissues and has high prevalence in the adult population. Periodontal pockets are ideal environments for subgingival bacterial biofilms, that interact with the supragingival oral cavity, mucosal tissues of the pocket and a peripheral circulatory system. Periodontal pockets have been found to harbor viral species such as the Herpes simplex viruses' family. Recently, the SARS-CoV-2 has gained major interest of the scientific/medical community as it caused a global pandemic (Covid-19) and paralyzed the globe with high figures of infected people worldwide. This virus behavior is still partially understood, and by analyzing some of its features we hypothesized that periodontal pocket could be a favorable anatomical niche for the virus and thus acting as a reservoir for SARS-CoV-2.
  • |*Betacoronavirus/isolation & purification/pathogenicity[MESH]
  • |Angiotensin-Converting Enzyme 2[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Testing[MESH]
  • |Clinical Laboratory Techniques[MESH]
  • |Coronavirus Infections/diagnosis/metabolism/*virology[MESH]
  • |Disease Reservoirs/*virology[MESH]
  • |Host Microbial Interactions[MESH]
  • |Humans[MESH]
  • |Models, Biological[MESH]
  • |Mouth Mucosa/metabolism/virology[MESH]
  • |Pandemics[MESH]
  • |Peptidyl-Dipeptidase A/metabolism[MESH]
  • |Periodontal Pocket/metabolism/*virology[MESH]
  • |Pneumonia, Viral/metabolism/*virology[MESH]
  • |Receptors, Virus/metabolism[MESH]


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