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10.21873/invivo.11954 http://scihub22266oqcxt.onion/10.21873/invivo.11954 32503822!8378035!32503822     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       In+Vivo 2020 ; 34 (3 Suppl): 1633-1636 Nephropedia Template TP {{tp|p=32503822|t=2020. Human Gene Sequences in SARS-CoV-2 and Other Viruses |pdf=|usr=}}{{32503822}} gab.com Text Human Gene Sequences in SARS-CoV-2 and Other Viruses JO: In Vivo http://www.kidney.de/pget.php?&tw=1&pmid=32503822 #FOAvip In a previous study, we identified a 117 base severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequence in the human genome with 94.6% identity. The sequence was in chromosome 1p within an intronic region of the netrin G1 (NTNG1) gene. The sequence matched a sequence in the SARS-CoV-2 Orf1b gene in non-structural protein 14 (NSP14), which is an exonuclease and NSP15, an endoribonuclease. In the current study we compared the human genome with other viral genomes to determine some of the characteristics of human sequences found in the latter. Most of the viruses had human sequences, but they were short. Hepatitis A and St Louis encephalitis had human sequences that were longer than the 117 base SARS-Cov-2 sequence, but they were in non-coding regions of the human genome. The SARS-Cov-2 sequence was the only long sequence found in a human gene (NTNG1). The related coronaviruses SARS-Cov had a 41 BP human sequence on chromosome 3 that was not part of a human gene, and MERS had no human sequence. The 117 base SARS-CoV-2 human sequence is relatively close to the viral spike sequence, separated only by NSP16, a 904 base sequence. The mechanism for SARS-CoV-2 infection is the binding of the virus spike protein to the membrane-bound form of angiotensin-converting enzyme 2 (ACE2) and internalization of the complex by the host cell. We have no explanation for the NSP14 and NSP15 SARS-Cov-2 sequences we observed here or how they might relate to infectiousness. Further studies are warranted. Twit Text FOAVip Human Gene Sequences in SARS-CoV-2 and Other Viruses ????In Vivo http://www.kidney.de/pget.php?&tw=1&pmid=32503822 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32503822 #FOAvip English Wikipedia <ref>{{Cite pmid|32503822}}</ref> Human Gene Sequences in SARS-CoV-2 and Other Viruses #MMPMID32503822 Lehrer S; Rheinstein PH In Vivo 2020[Jun]; 34 (3 Suppl): 1633-1636 PMID32503822show ga In a previous study, we identified a 117 base severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequence in the human genome with 94.6% identity. The sequence was in chromosome 1p within an intronic region of the netrin G1 (NTNG1) gene. The sequence matched a sequence in the SARS-CoV-2 Orf1b gene in non-structural protein 14 (NSP14), which is an exonuclease and NSP15, an endoribonuclease. In the current study we compared the human genome with other viral genomes to determine some of the characteristics of human sequences found in the latter. Most of the viruses had human sequences, but they were short. Hepatitis A and St Louis encephalitis had human sequences that were longer than the 117 base SARS-Cov-2 sequence, but they were in non-coding regions of the human genome. The SARS-Cov-2 sequence was the only long sequence found in a human gene (NTNG1). The related coronaviruses SARS-Cov had a 41 BP human sequence on chromosome 3 that was not part of a human gene, and MERS had no human sequence. The 117 base SARS-CoV-2 human sequence is relatively close to the viral spike sequence, separated only by NSP16, a 904 base sequence. The mechanism for SARS-CoV-2 infection is the binding of the virus spike protein to the membrane-bound form of angiotensin-converting enzyme 2 (ACE2) and internalization of the complex by the host cell. We have no explanation for the NSP14 and NSP15 SARS-Cov-2 sequences we observed here or how they might relate to infectiousness. Further studies are warranted. |*Genome, Viral[MESH] |Betacoronavirus/*genetics[MESH] |Chromosomes, Human, Pair 1/genetics[MESH] |Chromosomes, Human, Pair 3/genetics[MESH] |DNA Viruses/genetics[MESH] |Endoribonucleases[MESH] |Exoribonucleases/*genetics[MESH] |GPI-Linked Proteins/genetics[MESH] |Humans[MESH] |Middle East Respiratory Syndrome Coronavirus/genetics[MESH] |Netrins/genetics[MESH] |SARS-CoV-2[MESH] |Sequence Alignment[MESH] |Sequence Homology, Nucleic Acid[MESH] |Severe acute respiratory syndrome-related coronavirus/*genetics[MESH] |Species Specificity[MESH] |Viral Nonstructural Proteins/*genetics[MESH]Human Gene Sequences in SARS-CoV-2 and Other Viruses (epmc).pdf DeepDyve Pubget Overpricing