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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 In+Vivo 2020 ; 34 (3 Suppl): 1589-1592 Nephropedia Template TP
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Role of Interleukin-6 in Lung Complications in Patients With COVID-19: Therapeutic Implications #MMPMID32503815
Smetana K Jr; Brabek J
In Vivo 2020[Jun]; 34 (3 Suppl): 1589-1592 PMID32503815show ga
COVID-19 is viral respiratory infection with frequently fatal lung complications in the elderly or in people with serious comorbidities. Lung destruction appears to be associated with a cytokine storm related to an increased level of interleukin-6 (IL6). Therapeutic targeting of the interleukin-6 signaling pathway can attenuate such a cytokine storm and can be beneficial for patients with COVID-19 in danger of pulmonary failure. This article demonstrates the importance of IL6 in progression of disease and the possibility of inhibition of IL6 signaling in COVID-19 therapy.