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10.1136/bmjdrc-2020-001476 http://scihub22266oqcxt.onion/10.1136/bmjdrc-2020-001476 32503812!7298690!32503812     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMJ+Open+Diabetes+Res+Care 2020 ; 8 (1): ä Nephropedia Template TP {{tp|p=32503812|t=2020. Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study |pdf=|usr=}}{{32503812}} gab.com Text Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study JO: BMJ Open Diabetes Res Care http://www.kidney.de/pget.php?&tw=1&pmid=32503812 #FOAvip INTRODUCTION: With intense deficiency of medical resources during COVID-19 pandemic, risk stratification is of strategic importance. Blood glucose level is an important risk factor for the prognosis of infection and critically ill patients. We aimed to investigate the prognostic value of blood glucose level in patients with COVID-19. RESEARCH DESIGN AND METHODS: We collected clinical and survival information of 2041 consecutive hospitalized patients with COVID-19 from two medical centers in Wuhan. Patients without available blood glucose level were excluded. We performed multivariable Cox regression to calculate HRs of blood glucose-associated indexes for the risk of progression to critical cases/mortality among non-critical cases, as well as in-hospital mortality in critical cases. Sensitivity analysis were conducted in patient without diabetes. RESULTS: Elevation of admission blood glucose level was an independent risk factor for progression to critical cases/death among non-critical cases (HR=1.30, 95% CI 1.03 to 1.63, p=0.026). Elevation of initial blood glucose level of critical diagnosis was an independent risk factor for in-hospital mortality in critical cases (HR=1.84, 95% CI 1.14 to 2.98, p=0.013). Higher median glucose level during hospital stay or after critical diagnosis (>/=6.1 mmol/L) was independently associated with increased risks of progression to critical cases/death among non-critical cases, as well as in-hospital mortality in critical cases. Above results were consistent in the sensitivity analysis in patients without diabetes. CONCLUSIONS: Elevation of blood glucose level predicted worse outcomes in hospitalized patients with COVID-19. Our findings may provide a simple and practical way to risk stratify COVID-19 inpatients for hierarchical management, particularly where medical resources are in severe shortage during the pandemic. Twit Text FOAVip Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study ????BMJ Open Diabetes Res Care http://www.kidney.de/pget.php?&tw=1&pmid=32503812 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32503812 #FOAvip English Wikipedia <ref>{{Cite pmid|32503812}}</ref> Elevation of blood glucose level predicts worse outcomes in hospitalized patients with COVID-19: a retrospective cohort study #MMPMID32503812 Wu J; Huang J; Zhu G; Wang Q; Lv Q; Huang Y; Yu Y; Si X; Yi H; Wang C; Liu Y; Xiao H; Zhou Q; Liu X; Yang D; Guan X; Li Y; Peng S; Sung J; Xiao H BMJ Open Diabetes Res Care 2020[Jun]; 8 (1): ä PMID32503812show ga INTRODUCTION: With intense deficiency of medical resources during COVID-19 pandemic, risk stratification is of strategic importance. Blood glucose level is an important risk factor for the prognosis of infection and critically ill patients. We aimed to investigate the prognostic value of blood glucose level in patients with COVID-19. RESEARCH DESIGN AND METHODS: We collected clinical and survival information of 2041 consecutive hospitalized patients with COVID-19 from two medical centers in Wuhan. Patients without available blood glucose level were excluded. We performed multivariable Cox regression to calculate HRs of blood glucose-associated indexes for the risk of progression to critical cases/mortality among non-critical cases, as well as in-hospital mortality in critical cases. Sensitivity analysis were conducted in patient without diabetes. RESULTS: Elevation of admission blood glucose level was an independent risk factor for progression to critical cases/death among non-critical cases (HR=1.30, 95% CI 1.03 to 1.63, p=0.026). Elevation of initial blood glucose level of critical diagnosis was an independent risk factor for in-hospital mortality in critical cases (HR=1.84, 95% CI 1.14 to 2.98, p=0.013). Higher median glucose level during hospital stay or after critical diagnosis (>/=6.1 mmol/L) was independently associated with increased risks of progression to critical cases/death among non-critical cases, as well as in-hospital mortality in critical cases. Above results were consistent in the sensitivity analysis in patients without diabetes. CONCLUSIONS: Elevation of blood glucose level predicted worse outcomes in hospitalized patients with COVID-19. Our findings may provide a simple and practical way to risk stratify COVID-19 inpatients for hierarchical management, particularly where medical resources are in severe shortage during the pandemic. |*Betacoronavirus[MESH] |*Hospitalization[MESH] |Aged[MESH] |Blood Glucose/*analysis[MESH] |COVID-19[MESH] |Coronavirus Infections/*blood/*mortality/virology[MESH] |Critical Illness[MESH] |Disease Progression[MESH] |Female[MESH] |Follow-Up Studies[MESH] |Hospital Mortality[MESH] |Humans[MESH] |Hyperglycemia/*diagnosis[MESH] |Inpatients[MESH] |Length of Stay[MESH] |Male[MESH] |Middle Aged[MESH] |Pandemics[MESH] |Pneumonia, Viral/*blood/*mortality/virology[MESH] |Prognosis[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]Elevation of blood glucose level predicts worse outcomes in hospitaliz(epmc).pdf DeepDyve Pubget Overpricing