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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Hum+Vaccin+Immunother 2020 ; 16 (9): 2217-2218 Nephropedia Template TP
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Vaccine repurposing approach for preventing COVID 19: can MMR vaccines reduce morbidity and mortality? #MMPMID32501133
Anbarasu A; Ramaiah S; Livingstone P
Hum Vaccin Immunother 2020[Sep]; 16 (9): 2217-2218 PMID32501133show ga
The coronavirus disease (COVID-19) is resulting in millions of infected individuals with several hundred thousands dead throughout the world. Amidst all the havoc, one interesting observation in the present COVID-19 pandemic is the negligible symptoms in the young; particularly children below 10 years of age. We assume the extensive pediatric vaccination with MMR vaccines followed globally could have resulted in innate immune responses, e.g., induction of interferons (IFNs) and activated natural killer (NK) cells, thereby offering natural immunity against SARS-CoV-2 in the young population. Possible cross-protective innate immunity offered by MMR vaccination prompted us to suggest repurposing MMR vaccination for immuno-prophylaxis against COVID-19.