Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.3390/cells9061383 http://scihub22266oqcxt.onion/10.3390/cells9061383 32498376!7348784!32498376     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cells 2020 ; 9 (6): ä Nephropedia Template TP {{tp|p=32498376|t=2020. Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19 |pdf=|usr=}}{{32498376}} gab.com Text Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19 JO: Cells http://www.kidney.de/pget.php?&tw=1&pmid=32498376 #FOAvip The COVID-19 pandemic is progressing worldwide with an alarming death toll. There is an urgent need for novel therapeutic strategies to combat potentially fatal complications. Distinctive clinical features of severe COVID-19 include acute respiratory distress syndrome, neutrophilia, and cytokine storm, along with severe inflammatory response syndrome or sepsis. Here, we propose the putative role of enhanced neutrophil infiltration and the release of neutrophil extracellular traps, complement activation and vascular thrombosis during necroinflammation in COVID-19. Furthermore, we discuss how neutrophilic inflammation contributes to the higher mortality of COVID-19 in patients with underlying co-morbidities such as diabetes and cardiovascular diseases. This perspective highlights neutrophils as a putative target for the immunopathologic complications of severely ill COVID-19 patients. Development of the novel therapeutic strategies targeting neutrophils may help reduce the overall disease fatality rate of COVID-19. Twit Text FOAVip Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19 ????Cells http://www.kidney.de/pget.php?&tw=1&pmid=32498376 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32498376 #FOAvip English Wikipedia <ref>{{Cite pmid|32498376}}</ref> Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation in COVID-19 #MMPMID32498376 Tomar B; Anders HJ; Desai J; Mulay SR Cells 2020[Jun]; 9 (6): ä PMID32498376show ga The COVID-19 pandemic is progressing worldwide with an alarming death toll. There is an urgent need for novel therapeutic strategies to combat potentially fatal complications. Distinctive clinical features of severe COVID-19 include acute respiratory distress syndrome, neutrophilia, and cytokine storm, along with severe inflammatory response syndrome or sepsis. Here, we propose the putative role of enhanced neutrophil infiltration and the release of neutrophil extracellular traps, complement activation and vascular thrombosis during necroinflammation in COVID-19. Furthermore, we discuss how neutrophilic inflammation contributes to the higher mortality of COVID-19 in patients with underlying co-morbidities such as diabetes and cardiovascular diseases. This perspective highlights neutrophils as a putative target for the immunopathologic complications of severely ill COVID-19 patients. Development of the novel therapeutic strategies targeting neutrophils may help reduce the overall disease fatality rate of COVID-19. |Angiotensin-Converting Enzyme 2[MESH] |Animals[MESH] |Betacoronavirus/physiology[MESH] |COVID-19[MESH] |Cardiovascular Diseases/complications[MESH] |Coronavirus Infections/complications/drug therapy/*immunology/*pathology[MESH] |Diabetes Complications/virology[MESH] |Extracellular Traps/*immunology[MESH] |Humans[MESH] |Inflammation/immunology/pathology[MESH] |Necrosis/immunology/pathology[MESH] |Neutrophils/*immunology/metabolism[MESH] |Pandemics[MESH] |Peptidyl-Dipeptidase A/metabolism[MESH] |Pneumonia, Viral/complications/drug therapy/*immunology/*pathology[MESH]Neutrophils and Neutrophil Extracellular Traps Drive Necroinflammation(epmc).pdf DeepDyve Pubget Overpricing