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10.1111/liv.14557

http://scihub22266oqcxt.onion/10.1111/liv.14557
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32495496!7300742!32495496
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suck abstract from ncbi


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pmid32495496      Liver+Int 2020 ; 40 (8): 1860-1864
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  • Abnormal liver tests in patients hospitalized with Coronavirus disease 2019: Should we worry? #MMPMID32495496
  • Meszaros M; Meunier L; Morquin D; Klouche K; Fesler P; Malezieux E; Makinson A; Le Moing V; Reynes J; Pageaux GP
  • Liver Int 2020[Aug]; 40 (8): 1860-1864 PMID32495496show ga
  • While several studies from China have reported COVID-19-related liver injury, there are currently no data on liver dysfunction in hospitalized COVID-19 patients in Europe. The aim of this study was to describe the prevalence and predictive value of abnormal liver function in patients hospitalized with COVID-19. This was a retrospective cohort study of confirmed COVID-19 patients hospitalized in two referral hospitals in France. Clinical, biological and radiological data were collected and analysed. In all, 234 patients confirmed to have COVID-19 by RT-PCR were included. Liver function was abnormal in 66.6% of patients on admission. In multivariate logistic regression, abnormal liver test on admission were associated with in-hospital aggravation (OR = 4.1, 95% CI 1.5-10.8; P = .004) and mortality (OR 3.3; 95% CI = 1.04-10.5; P = .04). This study of liver tests in a European COVID-19 population confirms a high prevalence of abnormal liver tests on admission that are predictive of severe disease course and higher in-hospital mortality.
  • |*Betacoronavirus[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/drug therapy/*physiopathology[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Liver Function Tests[MESH]
  • |Liver/*physiopathology[MESH]
  • |Logistic Models[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/drug therapy/*physiopathology[MESH]
  • |Retrospective Studies[MESH]


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