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10.1186/s12967-020-02392-y

http://scihub22266oqcxt.onion/10.1186/s12967-020-02392-y
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32493510!7268185!32493510
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suck abstract from ncbi


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pmid32493510      J+Transl+Med 2020 ; 18 (1): 222
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  • SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines #MMPMID32493510
  • Salvatori G; Luberto L; Maffei M; Aurisicchio L; Roscilli G; Palombo F; Marra E
  • J Transl Med 2020[Jun]; 18 (1): 222 PMID32493510show ga
  • COVID-19 has rapidly spread all over the world, progressing into a pandemic. This situation has urgently impelled many companies and public research institutes to concentrate their efforts on research for effective therapeutics. Here, we outline the strategies and targets currently adopted in developing a vaccine against SARS-CoV-2. Based on previous evidence and experience with SARS and MERS, the primary focus has been the Spike protein, considered as the ideal target for COVID-19 immunotherapies.
  • |Animals[MESH]
  • |Antibodies, Viral/adverse effects/biosynthesis[MESH]
  • |Antibody-Dependent Enhancement/immunology[MESH]
  • |Betacoronavirus/genetics/*immunology/pathogenicity[MESH]
  • |COVID-19[MESH]
  • |COVID-19 Vaccines[MESH]
  • |Coronavirus Infections/epidemiology/genetics/immunology/*prevention & control[MESH]
  • |Humans[MESH]
  • |Pandemics/*prevention & control[MESH]
  • |Pneumonia, Viral/epidemiology/immunology/*prevention & control[MESH]
  • |SARS-CoV-2[MESH]
  • |Spike Glycoprotein, Coronavirus/chemistry/genetics/*immunology[MESH]
  • |Translational Research, Biomedical[MESH]


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