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10.1016/j.mehy.2020.109843 http://scihub22266oqcxt.onion/10.1016/j.mehy.2020.109843 32492560!7232076!32492560     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Hypotheses 2020 ; 143 (ä): 109843 Nephropedia Template TP {{tp|p=32492560|t=2020. Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?|pdf=|usr=}}{{32492560}} gab.com Text Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19 JO: Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=32492560 #FOAvip SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19. Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority. The paper proposes evidence for the potential use of diethylcarbamazine (DEC) in the treatment of COVID-19. DEC has inhibitory effects on arachidonic acid metabolism to prostaglandins, little known anti-viral effects on animal retroviruses and demonstrated anti-inflammatory actions in animal models of lung inflammation indicating the need to explore this hypothesis further. We believe this is the first time DEC is being proposed to treat COVID-19. Twit Text FOAVip Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19 ????Med Hypotheses http://www.kidney.de/pget.php?&tw=1&pmid=32492560 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32492560 #FOAvip English Wikipedia <ref>{{Cite pmid|32492560}}</ref> Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19? #MMPMID32492560 Abeygunasekera A; Jayasinghe S Med Hypotheses 2020[Oct]; 143 (ä): 109843 PMID32492560show ga SARS-CoV-2 virus has resulted in a devastating pandemic of COVID-19. Exploring compounds that could offer a breakthrough in treatment is the need of the hour. Re-positioning cheap, freely available and safe drugs is a priority. The paper proposes evidence for the potential use of diethylcarbamazine (DEC) in the treatment of COVID-19. DEC has inhibitory effects on arachidonic acid metabolism to prostaglandins, little known anti-viral effects on animal retroviruses and demonstrated anti-inflammatory actions in animal models of lung inflammation indicating the need to explore this hypothesis further. We believe this is the first time DEC is being proposed to treat COVID-19. |Anti-Inflammatory Agents/therapeutic use[MESH] |Antiviral Agents/therapeutic use[MESH] |Arachidonic Acid/metabolism[MESH] |Betacoronavirus[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Coronavirus Infections/*drug therapy[MESH] |Diethylcarbamazine/*therapeutic use[MESH] |Drug Repositioning[MESH] |Filaricides/therapeutic use[MESH] |Humans[MESH] |Inflammation[MESH] |Lung/pathology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*drug therapy[MESH] |Prostaglandins/metabolism[MESH]Is the anti-filarial drug diethylcarbamazine useful to treat COVID-19?(epmc).pdf DeepDyve Pubget Overpricing