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10.1017/S0950268820001181

http://scihub22266oqcxt.onion/10.1017/S0950268820001181
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32487271!7287303!32487271
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suck abstract from ncbi


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pmid32487271      Epidemiol+Infect 2020 ; 148 (ä): e108
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  • Epidemiological characteristics of COVID-19 patients in convalescence period #MMPMID32487271
  • Liu BM; Yang QQ; Zhao LY; Xie W; Si XY
  • Epidemiol Infect 2020[Jun]; 148 (ä): e108 PMID32487271show ga
  • This study aimed to investigate the clinical characteristics and to analyse the epidemiological features of coronavirus disease 2019 (COVID-19) patients during convalescence. In this study, we enrolled 71 confirmed cases of COVID-19 who were discharged from hospital and transferred to isolation wards from 6 February to 26 March 2020. They were all employees of Zhongnan Hospital of Wuhan University or their family members of which three cases were <18 years of age. Clinical data were collected and analysed statistically. Forty-one cases (41/71, 57.7%) comprised medical faculty, young and middle-aged patients (aged ?60 years) accounted for 81.7% (58/71). The average isolation time period for all adult patients was 13.8 +/- 6.1 days. During convalescence, RNA detection results of 35.2% patients (25/71) turned from negative to positive. The longest RNA reversed phase time was 7 days. In all, 52.9% of adult patients (36/68) had no obvious clinical symptoms, and the remaining ones had mild and non-specific clinical symptoms (e.g. cough, sputum, sore throat, disorders of the gastrointestinal tract etc.). Chest CT signs in 89.7% of adult patients (61/68) gradually improved, and in the others, the lesions were eventually absorbed and improved after short-term repeated progression. The main chest CT manifestations of adult patients were normal, GGO or fibre streak shadow, and six patients (8.8%) had extrapulmonary manifestations, but there was no significant correlation with RNA detection results (r = -0.008, P > 0.05). The drug treatment was mainly symptomatic support therapy, and antibiotics and antiviral drugs were ineffective. It is necessary to re-evaluate the isolation time and standard to terminate isolation for discharged COVID-19 patients.
  • |*Betacoronavirus[MESH]
  • |*Convalescence[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/diagnostic imaging/drug therapy/*epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/diagnostic imaging/drug therapy/*epidemiology[MESH]
  • |RNA, Viral/analysis[MESH]
  • |Radiography, Thoracic[MESH]
  • |SARS-CoV-2[MESH]


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