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10.3390/pathogens9060430 http://scihub22266oqcxt.onion/10.3390/pathogens9060430 32486188!7350360!32486188     free     free     free       Pathogens 2020 ; 9 (6): ä Nephropedia Template TP {{tp|p=32486188|t=2020. SARS-CoV-2 Infection and the Liver |pdf=|usr=}}{{32486188}} gab.com Text SARS-CoV-2 Infection and the Liver JO: Pathogens http://www.kidney.de/pget.php?&tw=1&pmid=32486188 #FOAvip A novel strain of coronoviridae (SARS-CoV-2) was reported in Wuhan China in December 2019. Initially, infection presented with a broad spectrum of symptoms which typically included muscle aches, fever, dry cough, and shortness of breath. SARS-CoV-2 enters cells via ACE2 receptors which are abundant throughout the respiratory tract. However, there is evidence that these receptors are abundant throughout the body, and just as abundant in cholangiocytes as alveolar cells, posing the question of possible direct liver injury. While liver enzymes and function tests do seem to be deranged in some patients, it is questionable if the injury is due to direct viral damage, drug-induced liver injury, hypoxia, or microthromboses. Likely, the injury is multifactoral, and management of infected patients with pre-existing liver disease should be taken into consideration. Ultimately, a vaccine is needed to aid in reducing cases of SARS-CoV-2 and providing immunity to the general population. However, while considering the types of vaccines available, safety concerns, particularly of RNA- or DNA-based vaccines, need to be addressed. Twit Text FOAVip SARS-CoV-2 Infection and the Liver ????Pathogens http://www.kidney.de/pget.php?&tw=1&pmid=32486188 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32486188 #FOAvip English Wikipedia <ref>{{Cite pmid|32486188}}</ref> SARS-CoV-2 Infection and the Liver #MMPMID32486188 Morgan K; Samuel K; Vandeputte M; Hayes PC; Plevris JN Pathogens 2020[May]; 9 (6): ä PMID32486188show ga A novel strain of coronoviridae (SARS-CoV-2) was reported in Wuhan China in December 2019. Initially, infection presented with a broad spectrum of symptoms which typically included muscle aches, fever, dry cough, and shortness of breath. SARS-CoV-2 enters cells via ACE2 receptors which are abundant throughout the respiratory tract. However, there is evidence that these receptors are abundant throughout the body, and just as abundant in cholangiocytes as alveolar cells, posing the question of possible direct liver injury. While liver enzymes and function tests do seem to be deranged in some patients, it is questionable if the injury is due to direct viral damage, drug-induced liver injury, hypoxia, or microthromboses. Likely, the injury is multifactoral, and management of infected patients with pre-existing liver disease should be taken into consideration. Ultimately, a vaccine is needed to aid in reducing cases of SARS-CoV-2 and providing immunity to the general population. However, while considering the types of vaccines available, safety concerns, particularly of RNA- or DNA-based vaccines, need to be addressed. äSARS-CoV-2 Infection and the Liver (epmc).pdf DeepDyve Pubget Overpricing