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10.3390/ijms21113875 http://scihub22266oqcxt.onion/10.3390/ijms21113875 32485905!7312925!32485905     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2020 ; 21 (11): ä Nephropedia Template TP {{tp|p=32485905|t=2020. Continuum Models of Membrane Fusion: Evolution of the Theory |pdf=|usr=}}{{32485905}} gab.com Text Continuum Models of Membrane Fusion: Evolution of the Theory JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32485905 #FOAvip Starting from fertilization, through tissue growth, hormone secretion, synaptic transmission, and sometimes morbid events of carcinogenesis and viral infections, membrane fusion regulates the whole life of high organisms. Despite that, a lot of fusion processes still lack well-established models and even a list of main actors. A merger of membranes requires their topological rearrangements controlled by elastic properties of a lipid bilayer. That is why continuum models based on theories of membrane elasticity are actively applied for the construction of physical models of membrane fusion. Started from the view on the membrane as a structureless film with postulated geometry of fusion intermediates, they developed along with experimental and computational techniques to a powerful tool for prediction of the whole process with molecular accuracy. In the present review, focusing on fusion processes occurring in eukaryotic cells, we scrutinize the history of these models, their evolution and complication, as well as open questions and remaining theoretical problems. We show that modern approaches in this field allow continuum models of membrane fusion to stand shoulder to shoulder with molecular dynamics simulations, and provide the deepest understanding of this process in multiple biological systems. Twit Text FOAVip Continuum Models of Membrane Fusion: Evolution of the Theory ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32485905 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32485905 #FOAvip English Wikipedia <ref>{{Cite pmid|32485905}}</ref> Continuum Models of Membrane Fusion: Evolution of the Theory #MMPMID32485905 Akimov SA; Molotkovsky RJ; Kuzmin PI; Galimzyanov TR; Batishchev OV Int J Mol Sci 2020[May]; 21 (11): ä PMID32485905show ga Starting from fertilization, through tissue growth, hormone secretion, synaptic transmission, and sometimes morbid events of carcinogenesis and viral infections, membrane fusion regulates the whole life of high organisms. Despite that, a lot of fusion processes still lack well-established models and even a list of main actors. A merger of membranes requires their topological rearrangements controlled by elastic properties of a lipid bilayer. That is why continuum models based on theories of membrane elasticity are actively applied for the construction of physical models of membrane fusion. Started from the view on the membrane as a structureless film with postulated geometry of fusion intermediates, they developed along with experimental and computational techniques to a powerful tool for prediction of the whole process with molecular accuracy. In the present review, focusing on fusion processes occurring in eukaryotic cells, we scrutinize the history of these models, their evolution and complication, as well as open questions and remaining theoretical problems. We show that modern approaches in this field allow continuum models of membrane fusion to stand shoulder to shoulder with molecular dynamics simulations, and provide the deepest understanding of this process in multiple biological systems. |*Membrane Fusion[MESH] |*Molecular Dynamics Simulation[MESH] |Animals[MESH] |Cell Membrane/*physiology[MESH] |Elasticity[MESH] |Humans[MESH] |Lipid Bilayers/*chemistry[MESH] |Models, Biological[MESH]Continuum Models of Membrane Fusion: Evolution of the Theory (epmc).pdf DeepDyve Pubget Overpricing