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10.1016/j.jcv.2020.104475

http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104475
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32485619!7250074!32485619
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suck abstract from ncbi


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pmid32485619      J+Clin+Virol 2020 ; 129 (ä): 104475
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  • Epidemiological and clinical features of 200 hospitalized patients with corona virus disease 2019 outside Wuhan, China: A descriptive study #MMPMID32485619
  • Yang L; Liu J; Zhang R; Li M; Li Z; Zhou X; Hu C; Tian F; Zhou F; Lei Y
  • J Clin Virol 2020[Aug]; 129 (ä): 104475 PMID32485619show ga
  • BACKGROUND: The recent outbreak of coronavirus disease 2019 (COVID-19) has spread worldwide, with especially severe epidemics occurring in cities across China. OBJECTIVES: To report the epidemiological and clinical futures of the 200 patients infected with COVID-19 in Yichang, Hubei Province, China. STUDY DESIGN: 200 patients confirmed with COVID-19 in a designated hospital in Yichang from Jan 30 to Feb 8, 2020 were investigated retrospectively. The epidemiological data and clinical characteristics were collected. The data between the ICU patients and non-ICU patients were compared. The patients were followed up till Feb 26, 2020. RESULTS: Of the 200 hospitalized patients with COVID-19, 98 (49.0 %) were male, and the mean age was 55 years. Eighty-seven (43.5 %) had no linkage to Wuhan or contact history. Familial clustering was found in 34 patients. Sixtyfive (32.5 %) suffered from chronic diseases. The common symptoms included fever (171[85.5 %]), cough (116[58.0 %]), and fatigue (64[32 %]). Most patients had lymphopenia. One hundred and seventy-two (86 %) patients showed typical imaging findings of viral pneumonia. Most patients received antiviral, antibiotic, and corticosteroid treatment. Compared with the non-ICU patients, 29 (14.5 %) patients in the ICU were older and more likely to show dyspnea and complications including ARDS. As of Feb 26, 15 (51.7 %) patients in the ICU had died. CONCLUSIONS: The COVID-19 infection was of clustering onset and can cause severe respiratory disease and even death. The mortality of ICU patients with COVID-19 was considerably high.
  • |*Disease Outbreaks[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Animals[MESH]
  • |Betacoronavirus/*isolation & purification[MESH]
  • |COVID-19[MESH]
  • |China/epidemiology[MESH]
  • |Cities/epidemiology[MESH]
  • |Coronavirus Infections/*epidemiology/*pathology[MESH]
  • |Demography[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Hospitalization[MESH]
  • |Hospitals[MESH]
  • |Humans[MESH]
  • |Inpatients[MESH]
  • |Intensive Care Units[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*epidemiology/*pathology[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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