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Current Perspective of Antiviral Strategies against COVID-19 #MMPMID32485102
Ahidjo BA; Loe MWC; Ng YL; Mok CK; Chu JJH
ACS Infect Dis 2020[Jul]; 6 (7): 1624-1634 PMID32485102show ga
COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020. This novel coronavirus disease, caused by the SARS-CoV-2 virus, has resulted in severe and unprecedented social and economic disruptions globally. Since the discovery of COVID-19 in December 2019, numerous antivirals have been tested for efficacy against SARS-CoV-2 in vitro and also clinically to treat this disease. This review article discusses the main antiviral strategies currently employed and summarizes reported in vitro and in vivo efficacies of key antiviral compounds in use.