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COVID-19 in Parkinson s Disease Patients Living in Lombardy, Italy #MMPMID32484584
Fasano A; Cereda E; Barichella M; Cassani E; Ferri V; Zecchinelli AL; Pezzoli G
Mov Disord 2020[Jul]; 35 (7): 1089-1093 PMID32484584show ga
BACKGROUND: It is unknown whether patients with PD are at greater risk of COVID-19, what their risk factors are, and whether their clinical manifestations differ from the general population. OBJECTIVES: The study aimed to address all these issues. METHODS: In a case-controlled survey, we interviewed 1,486 PD patients attending a single tertiary center in Lombardy, Italy and 1,207 family members (controls). RESULTS: One hundred five (7.1%) and 92 controls (7.6%) were identified as COVID-19 cases. COVID-19 patients were younger, more likely to suffer from chronic obstructive pulmonary disease, to be obese, and vitamin D nonsupplemented than unaffected patients. Six patients (5.7%) and 7 family members (7.6%) died from COVID-19. Patients were less likely to report shortness of breath and require hospitalization. CONCLUSIONS: In an unselected large cohort of nonadvanced PD patients, COVID-19 risk and mortality did not differ from the general population, but symptoms appeared to be milder. The possible protective role of vitamin D supplementation warrants future studies. (c) 2020 International Parkinson and Movement Disorder Society.
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Mov+Disord 2020 ; 35 (7): 1089-1093
