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10.1021/acscentsci.0c00489 http://scihub22266oqcxt.onion/10.1021/acscentsci.0c00489 32483554!7202249!32483554     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32483554&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       ACS+Cent+Sci 2020 ; 6 (5): 672-683 Nephropedia Template TP {{tp|p=32483554|t=2020. Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 |pdf=|usr=}}{{32483554}} gab.com Text Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 JO: ACS Cent Sci http://www.kidney.de/pget.php?&tw=1&pmid=32483554 #FOAvip The global pandemic of SARS-CoV-2, the causative viral pathogen of COVID-19, has driven the biomedical community to action-to uncover and develop antiviral interventions. One potential therapeutic approach currently being evaluated in numerous clinical trials is the agent remdesivir, which has endured a long and winding developmental path. Remdesivir is a nucleotide analogue prodrug that perturbs viral replication, originally evaluated in clinical trials to thwart the Ebola outbreak in 2014. Subsequent evaluation by numerous virology laboratories demonstrated the ability of remdesivir to inhibit coronavirus replication, including SARS-CoV-2. Here, we provide an overview of remdesivir's discovery, mechanism of action, and the current studies exploring its clinical effectiveness. Twit Text FOAVip Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 ????ACS Cent Sci http://www.kidney.de/pget.php?&tw=1&pmid=32483554 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32483554 #FOAvip English Wikipedia <ref>{{Cite pmid|32483554}}</ref> Remdesivir: A Review of Its Discovery and Development Leading to Emergency Use Authorization for Treatment of COVID-19 #MMPMID32483554 Eastman RT; Roth JS; Brimacombe KR; Simeonov A; Shen M; Patnaik S; Hall MD ACS Cent Sci 2020[May]; 6 (5): 672-683 PMID32483554show ga The global pandemic of SARS-CoV-2, the causative viral pathogen of COVID-19, has driven the biomedical community to action-to uncover and develop antiviral interventions. One potential therapeutic approach currently being evaluated in numerous clinical trials is the agent remdesivir, which has endured a long and winding developmental path. Remdesivir is a nucleotide analogue prodrug that perturbs viral replication, originally evaluated in clinical trials to thwart the Ebola outbreak in 2014. Subsequent evaluation by numerous virology laboratories demonstrated the ability of remdesivir to inhibit coronavirus replication, including SARS-CoV-2. Here, we provide an overview of remdesivir's discovery, mechanism of action, and the current studies exploring its clinical effectiveness. ?Remdesivir: A Review of Its Discovery and Development Leading to Emerg(epmc).pdf DeepDyve Pubget Overpricing