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10.1021/acssensors.0c00979 http://scihub22266oqcxt.onion/10.1021/acssensors.0c00979 32482077!ä!32482077 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       ACS+Sens 2020 ; 5 (6): 1506-1513 Nephropedia Template TP {{tp|p=32482077|t=2020. Biosensors for Managing the COVID-19 Cytokine Storm: Challenges Ahead |pdf=|usr=}}{{32482077}} gab.com Text Biosensors for Managing the COVID-19 Cytokine Storm: Challenges Ahead JO: ACS Sens http://www.kidney.de/pget.php?&tw=1&pmid=32482077 #FOAvip The global COVID-19 pandemic has oversaturated many intensive care units to the point of collapse, leading to enormous spikes in death counts. Before critical care becomes a necessity, identifying patients who are likely to become critically ill and providing prompt treatment is a strategy to avoid ICU oversaturation. There is a consensus that a hyperinflammatory syndrome or a "cytokine storm" is responsible for poor outcomes in COVID-19. Measuring cytokine levels at the point of care is required in order to better understand this process. In this Perspective, we summarize the main events behind the cytokine storm in COVID-19 as well as current experimental treatments. We advocate for a new biosensor-enabled paradigm to personalize the management of COVID-19 and stratify patients. Biosensor-guided dosing and timing of immunomodulatory therapies could maximize the benefits of these anti-inflammatory treatments while minimizing deleterious effects. Biosensors will also be essential in order to detect complications such as coinfections and sepsis, which are common in immunosuppressed patients. Finally, we propose the ideal features of these biosensors using some prototypes from the recent literature as examples. Multisensors, lateral flow tests, mobile biosensors, and wearable biosensors are seen as key players for precision medicine in COVID-19. Twit Text FOAVip Biosensors for Managing the COVID-19 Cytokine Storm: Challenges Ahead ????ACS Sens http://www.kidney.de/pget.php?&tw=1&pmid=32482077 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32482077 #FOAvip English Wikipedia <ref>{{Cite pmid|32482077}}</ref> Biosensors for Managing the COVID-19 Cytokine Storm: Challenges Ahead #MMPMID32482077 Russell SM; Alba-Patino A; Baron E; Borges M; Gonzalez-Freire M; de la Rica R ACS Sens 2020[Jun]; 5 (6): 1506-1513 PMID32482077show ga The global COVID-19 pandemic has oversaturated many intensive care units to the point of collapse, leading to enormous spikes in death counts. Before critical care becomes a necessity, identifying patients who are likely to become critically ill and providing prompt treatment is a strategy to avoid ICU oversaturation. There is a consensus that a hyperinflammatory syndrome or a "cytokine storm" is responsible for poor outcomes in COVID-19. Measuring cytokine levels at the point of care is required in order to better understand this process. In this Perspective, we summarize the main events behind the cytokine storm in COVID-19 as well as current experimental treatments. We advocate for a new biosensor-enabled paradigm to personalize the management of COVID-19 and stratify patients. Biosensor-guided dosing and timing of immunomodulatory therapies could maximize the benefits of these anti-inflammatory treatments while minimizing deleterious effects. Biosensors will also be essential in order to detect complications such as coinfections and sepsis, which are common in immunosuppressed patients. Finally, we propose the ideal features of these biosensors using some prototypes from the recent literature as examples. Multisensors, lateral flow tests, mobile biosensors, and wearable biosensors are seen as key players for precision medicine in COVID-19. |*Betacoronavirus[MESH] |*Immunomodulation[MESH] |*Inflammation[MESH] |Biosensing Techniques/*methods[MESH] |COVID-19[MESH] |Coronavirus Infections/diagnosis/immunology/*therapy[MESH] |Cytokines/*analysis/immunology[MESH] |Humans[MESH] |Interleukin-6/analysis/immunology[MESH] |Pandemics[MESH] |Pneumonia, Viral/diagnosis/immunology/*therapy[MESH] |Precision Medicine[MESH] |SARS-CoV-2[MESH]Biosensors for Managing the COVID-19 Cytokine Storm: Challenges Ahead (epmc).pdf DeepDyve Pubget Overpricing