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10.3390/ijms21113837 http://scihub22266oqcxt.onion/10.3390/ijms21113837 32481620!7312103!32481620     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Sci 2020 ; 21 (11): ä Nephropedia Template TP {{tp|p=32481620|t=2020. TRPV4: A Physio and Pathophysiologically Significant Ion Channel |pdf=|usr=}}{{32481620}} gab.com Text TRPV4: A Physio and Pathophysiologically Significant Ion Channel JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32481620 #FOAvip Transient Receptor Potential (TRP) channels are a family of ion channels whose members are distributed among all kinds of animals, from invertebrates to vertebrates. The importance of these molecules is exemplified by the variety of physiological roles they play. Perhaps, the most extensively studied member of this family is the TRPV1 ion channel; nonetheless, the activity of TRPV4 has been associated to several physio and pathophysiological processes, and its dysfunction can lead to severe consequences. Several lines of evidence derived from animal models and even clinical trials in humans highlight TRPV4 as a therapeutic target and as a protein that will receive even more attention in the near future, as will be reviewed here. Twit Text FOAVip TRPV4: A Physio and Pathophysiologically Significant Ion Channel ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=32481620 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32481620 #FOAvip English Wikipedia <ref>{{Cite pmid|32481620}}</ref> TRPV4: A Physio and Pathophysiologically Significant Ion Channel #MMPMID32481620 Rosenbaum T; Benitez-Angeles M; Sanchez-Hernandez R; Morales-Lazaro SL; Hiriart M; Morales-Buenrostro LE; Torres-Quiroz F Int J Mol Sci 2020[May]; 21 (11): ä PMID32481620show ga Transient Receptor Potential (TRP) channels are a family of ion channels whose members are distributed among all kinds of animals, from invertebrates to vertebrates. The importance of these molecules is exemplified by the variety of physiological roles they play. Perhaps, the most extensively studied member of this family is the TRPV1 ion channel; nonetheless, the activity of TRPV4 has been associated to several physio and pathophysiological processes, and its dysfunction can lead to severe consequences. Several lines of evidence derived from animal models and even clinical trials in humans highlight TRPV4 as a therapeutic target and as a protein that will receive even more attention in the near future, as will be reviewed here. |Animals[MESH] |Calcium/metabolism[MESH] |Cattle[MESH] |Endothelium, Vascular/metabolism[MESH] |Humans[MESH] |Kidney/metabolism[MESH] |Mice[MESH] |Microcirculation[MESH] |Pain/metabolism[MESH] |Permeability[MESH] |Prognosis[MESH] |Protein Domains[MESH] |Rats[MESH] |Retinal Vessels[MESH] |Skin/metabolism[MESH]TRPV4: A Physio and Pathophysiologically Significant Ion Channel (epmc).pdf DeepDyve Pubget Overpricing