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10.1097/MD.0000000000020370

http://scihub22266oqcxt.onion/10.1097/MD.0000000000020370
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32481333!7249955!32481333
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suck abstract from ncbi


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pmid32481333      Medicine+(Baltimore) 2020 ; 99 (21): e20370
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  • CT manifestations of the coronavirus disease 2019 of imported infection versus second-generation infection in patients outside the original district (Wuhan, China) of this disease: An observational study #MMPMID32481333
  • Wu YP; Cao JM; Chen TW; Li R; Liu FJ; Zeng Y; Zhang XM; Mu QW; Li HJ
  • Medicine (Baltimore) 2020[May]; 99 (21): e20370 PMID32481333show ga
  • To explore the discrepancy in computed tomography (CT) manifestations of the coronavirus disease 2019 (COVID-19) in patients outside the original district (Wuhan, China) between cases with imported infection and second-generation infection, 22 patients with COVID-19 from 2 hospitals in Nanchong, China, 938 km away from the original district (Wuhan, China) of this disease were enrolled. All patients underwent initial and follow-up CT after admission during the treatment, and were divided into 2 groups. Group A and B were composed of 15 patients with a history of exposure to the original district (Wuhan, China) in short-term (i.e., imported infection), and 7 with a close contact with the patients with confirmed COVID-19 or with the healthy individuals from the original district (i.e., second-generation infection), respectively. Initial CT features including extent score and density score between groups were statistically compared. We found that all patients in group A and 3 of 7 patients in group B had abnormal CT findings while 4 of 7 patients in group B had not. Patients with abnormal CT findings were more frequent in group A than in group B (P < .05). On initial CT, pure ground glass opacity (GGO), and GGO with consolidation and/or other abnormalities were found in 20% (3/15) and 80% (12/15) patients in group A, respectively, while 1 (14.3%), 2 (28.6%), and 4 (57.1%) had pure GGOs, GGO with focal consolidation, and normal CT appearances in Group B, respectively. Patients with extent and density scores of >/=5 were more frequent in group A than in group B (all P-values < .01). Additionally, 3 of 4 (75%) patients with normal initial CT findings had focal pure GGO lesions on follow-up. In conclusion, COVID-19 in patients with a history of exposure to the original district can be severer than with the second-generation infection on CT.
  • |*Tomography, X-Ray Computed[MESH]
  • |Adult[MESH]
  • |COVID-19[MESH]
  • |China[MESH]
  • |Communicable Diseases, Imported/*diagnostic imaging/*virology[MESH]
  • |Coronavirus Infections/*diagnostic imaging[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Pandemics[MESH]


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