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  • SARS-CoV-2 entry in host cells-multiple targets for treatment and prevention #MMPMID32479856
  • Mahmoud IS; Jarrar YB; Alshaer W; Ismail S
  • Biochimie 2020[Aug]; 175 (ä): 93-98 PMID32479856show ga
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new viral disease that has gained global attention owing to its ability to provoke community and health-care-associated outbreaks of severe infections in human populations. The virus poses serious challenges to clinical management because there are still no approved anti- SARS-CoV-2 drugs available. In this mini-review, we summarize the much updated published reports that demonstrate the mechanism of SARS-CoV-2 entry into host cells, and discuss the availability and development of attractive host-based therapeutic options for SARS-CoV-2 infections.
  • |*Virus Internalization[MESH]
  • |Betacoronavirus/*metabolism/*pathogenicity[MESH]
  • |COVID-19[MESH]
  • |Coronavirus Infections/*metabolism/therapy[MESH]
  • |Host-Pathogen Interactions/*physiology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Pneumonia, Viral/*metabolism/therapy[MESH]
  • |SARS-CoV-2[MESH]

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  • suck abstract from ncbi

    93 ä.175 2020