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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Am+J+Transplant 2020 ; 20 (11): 3225-3233 Nephropedia Template TP
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Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: A case series from the United States #MMPMID32476258
Fung M; Chiu CY; DeVoe C; Doernberg SB; Schwartz BS; Langelier C; Henrich TJ; Yokoe D; Davis J; Hays SR; Chandran S; Kukreja J; Ng D; Prostko J; Taylor R; Reyes K; Bainbridge E; Bond A; Chin-Hong P; Babik JM
Am J Transplant 2020[Nov]; 20 (11): 3225-3233 PMID32476258show ga
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS coronavirus 2 (SARS-CoV-2) has caused significant morbidity and mortality for patients and stressed healthcare systems worldwide. The clinical features, disease course, and serologic response of COVID-19 among immunosuppressed patients such as solid organ transplant (SOT) recipients, who are at presumed risk for more severe disease, are not well characterized. We describe our institutional experience with COVID-19 among 10 SOT patients, including the clinical presentation, treatment modalities, and outcomes of 7 renal transplant recipients, 1 liver transplant recipient, 1 heart transplant recipient, and 1 lung transplant recipient. In addition, we report the serologic response in SOT recipients, documenting a positive IgG response in all 7 hospitalized patients. We also review the existing literature on COVID-19 in SOT recipients to consolidate the current knowledge on COVID-19 in the SOT population for the transplant community.